“…Longstanding lipomatous lesions been documented at least 8 cm in size, possibly leading to unacceptable aesthetics, and various oral dysfunctional activities involving speech, swallowing, mastication and ability to wear a denture 3,6 . Moreover, continued expansion of oral and maxillofacial lipomas has led to hypoglossal nerve palsy; obstructive sleep apnoea; and diminished adequate nutritional intake, possibly leading to weight loss, electrolyte imbalance and an increased risk for infection (especially among immunocompromised and immunosenescent individuals) 7–9 . Furthermore, buccal mucosal lipomas near the plane of occlusion and lipomas along the lateral border of the tongue may become repeated targets of injury while eating and cause pain, promoting aggregations of fibrous connective tissue and possible mucosal ulceration, as acknowledged by the featured patient and corroborated histologically 6 …”