Oral Malignant Melanoma

A synchronous presentation of malignant melanoma and dermatofibrosarcoma protuberans in a Nigerian female: A case report

“…Although the association between the two lesions may most likely be coincidental, long exposure to environmental causative agents, hereditary factors, and reduced immunity from long-standing malignancy may increase the risk of other primary neoplasms occurring [ 9 , 16 ]. Whereas the etiology of oral mucous melanoma largely remains unknown, denture irritation, use of tobacco, alcohol, race, exposure to sunlight, and many other etiologic factors have been suggested as possible causes of palatal melanoma, however, evidence to support this remains scarce [ 8 , 15 , 17 ]. Epitheloid melanocytoma is a rare low-grade variant of melanoma with indolent behavior and a relatively good prognosis but is known to have the potential to transform to melanoma which appears to agree with our case [ 18 , 19 ].…”