2013
DOI: 10.1111/odi.12105
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Oral manifestations and their treatment in Sjögren′s syndrome

Abstract: Sjögren's syndrome (SS) is a complex, chronic, systemic, autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands, leading to dryness of the oral and ocular mucosae. Several factors have been studied that could explain the glandular hypofunction primarily related to water transport. Recent reports have shown alterations in secretory route and trafficking in labial salivary glands, explaining alterations in the saliva quality. The decrease in salivary flow and qual… Show more

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Cited by 52 publications
(38 citation statements)
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References 99 publications
(113 reference statements)
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“…However in patients with pSS due to xerostomia there is a difficulty in the prosthesis retention causing mucosal pain and irritation. Thus the speech is less noticeable [24].…”
Section: Other Communication Disorders and Dysphagiamentioning
confidence: 99%
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“…However in patients with pSS due to xerostomia there is a difficulty in the prosthesis retention causing mucosal pain and irritation. Thus the speech is less noticeable [24].…”
Section: Other Communication Disorders and Dysphagiamentioning
confidence: 99%
“…The increase in the number of teeth affected by caries causes frequent visits to the dentistry clinic and usually they have more tooth loss or restored comparing to healthy individuals [24]. The use of prosthesis due to tooth loss is also impaired due to xerostomia and the number of teeth restored is frequently very high and expensive, especially in older patients [4].…”
Section: Oral Manifestations and Communicationmentioning
confidence: 99%
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“…A Síndrome de Sjögren (SS) é descrita na literatura como uma doença crônica, sistêmica, autoimune (González et al, 2014) que afeta diversas glândulas, principalmente as lacrimais e salivares, causando sensação de olhos e boca secos (de Paiva, Rocha, 2015) a qual pode ser acompanhada por envolvimento extraglandular, como vasculite, neuropatia (de Paiva, Rocha, 2015), polissinovites (Maciel et al, 2016) e comprometimentos em outros órgãos internos (Kassan e Moutsopoulos, 2004).…”
Section: Introductionunclassified