Oral manifestations associated with COVID-19 disease: An observational cross sectional study

Chawla, Jitendra; Navaneeth, Y; Bakshi, Satvinder Singh; Kalidoss, Vinoth Kumar; Yadav, Shikha; Polineni, Swapnika; Jayam, Cheranjeevi

doi:10.1016/j.jobcr.2022.03.008

Cited by 14 publications

(29 citation statements)

References 23 publications

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“…Our study also showed most of the individuals manifesting dry mouth in 18 individuals (31.03%) besides taste loss and this also goes in agreement with the above-mentioned cross-sectional study and other study from India that showed xerostomia in about 28% of individuals. There have been other studies also that show xerostomia as one of the oral manifestations of COVID 19 [28][29][30]. The xerostomia could have occurred due to the fever and dehydration.…”

Section: Discussionmentioning

confidence: 94%

The Retrospective Pilot Study of the Prevalence of Olfactory Dysfunction or Loss of Smell, Loss of Taste and Oral Manifestations among COVID-19 Positive Health Workers in Muscat, Oman

Saraf¹

2022

Int J Oral Dent Health

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A retrospective study evaluating the prevalence of loss of smell, loss of taste and oral manifestations was carried out by framing an online questionnaire and disseminated among the health care workers including medical and dental students, who were afflicted with COVID-19. Objective:The objective of this study was to find out the prevalence of the loss of smell, loss of taste (LOST) and oral manifestations and whether these (LOST & Oral manifestations) can be the premonitory manifestations and also whether these can predict the prognosis of COVID-19 disease.Result: Our study showed that the loss of smell, loss of taste and dry mouth did occur before the other symptoms considerably in the COVID-19 infected health workers. All the infected health workers were in home quarantine phase and not hospitalized during the occurrence of COVID-19. Conclusion:The loss of smell, loss of taste and oral manifestations can be the prodromal signs of COVID-19 and may be used as a screening tool to predict the severity of the disease.

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Section: Discussionmentioning

confidence: 94%

The Retrospective Pilot Study of the Prevalence of Olfactory Dysfunction or Loss of Smell, Loss of Taste and Oral Manifestations among COVID-19 Positive Health Workers in Muscat, Oman

Saraf¹

2022

Int J Oral Dent Health

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“…Tiesiogi-nis neurosensorinių skonio pojūčių sutrikimas, galintis atsirasti dėl viruso kolonizacijos, gali lemti skonio disfunkciją. Pagal atrinktų tyrimų duomenis, tiriamiesiems pasireiškė skirtingo pobūdžio skonio pokyčiai: ageuzija, hipogeuzija arba disgeuzija [2,3,6,11]. E. Bardellini ir kiti [19] nurodė, kad skonio ir uoslės pokyčiai kartais pasireiškė anksčiau, nei kvėpavimo takų simptomai.…”

Section: Rezultatų Aptarimasunclassified

“…Manoma, kad skonio ir uoslės pokyčiai yra specifiniai šiai ligai. COVID-19 sergančiųjų kserostomijos dažnio pasireiškimo intervalas buvo nuo 0,3% iki 83,9% [2, 6,10,11,13,15,16,20]. Keletas autorių nurodė, kad kai kuriais atvejais kserostomija pasireiškė likus keletui dienų iki bet kokių kitų simptomų atsiradimo, kartu su kitais simptomais arba 1-2 dienos po jų atsiradimo [11,22].…”

Section: Rezultatų Aptarimasunclassified

Sergančiųjų Covid-19 Burnos Pakitimų Ypatumai

Vaitkevičienė¹,

Žukauskienė²,

Vaitkevičius³

2023

Health Sciences

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COVID-19 ligą sukelia su oro lašeliais ar per nešvarias rankas į organizmą patenkantis SARS-CoV-2 virusas, kuris jungiasi prie ląstelių AKF2 (angiotenziną konvertuojančio fermento 2) receptorių. COVID-19 infekcijos sąlygoti patologiniai burnos pakitimai gali būti specifinės klinikinės išraiškos, skirtis pasireiškimo dažniu ir lokalizacija, priklausyti nuo ligos sunkumo. Tyrimo tikslas – išanalizuoti sergančiųjų COVID-19 infekcija burnos pakitimų ypatumus. Tyrimo medžiaga ir metodai. Mokslinės literatūros paieška atlikta elektroniniu būdu PubMed, ClinicalKey ir Cochrane duomenų bazėje. Taikant PRISMA kriterijus, atrinkti viso teksto straipsniai anglų kalba, aprašantys daugiau nei vieno sergančiojo COVID-19 burnos pakitimų tyrimo atvejį ir atlikta analizė. Tiriamasis laikotarpis nuo 2021 m. iki 2022 m. kovo mėnesio. Rezultatai. Analizei atrinkta 16 straipsnių. Liežuvyje (36,2%), lūpose (22%), skruostų gleivinėje (13,4%) patologiniai pakitimai stebėti dažniau, nei kitose burnos vietose. Sergančiųjų COVID-19 dažniausi nustatyti burnos pakitimai buvo opos (32,2%), kandidamikozė (11,3%), eritema (9,9%). Nepriklausomai nuo ligos sunkumo ir formos, vyraujantis burnos infekcijos simptomas buvo skonio pokyčiai (67,1%). Išvada. COVID-19 infekcija dažniausiai sukelia vyraujantį specifinį skonio pokyčio simptomą ir nespecifinius burnos pakitimus (opas). Liežuvio pakitimai stebimi dažniau nei kitose burnos gleivinės vietose

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“… 6 Other clinical manifestations of Covid‐19 such as ulcers, vesicles, vesicular bleeding, necrotizing gingivitis, desquamative gingivitis, which have been reported to involve periodontal structures/mucosa remain unclear to be directly associated with SARS‐CoV‐2 infection. 5 , 7 , 8 , 9 , 10 These symptoms are rather ascribed to immune dysfunction associated with SARS‐CoV‐2 infection, superinfection with other microorganisms and disease‐related emotional stress. Long‐term inflammatory process observed in Covid‐19 patients may produce pathological responses in periodontal tissues leading to fibrinogen degradation and triggering coagulation cascade.…”

Section: Periodontal Manifestations In Covid‐19 Patients?mentioning

confidence: 99%

“…The degree of disturbed taste varies, from abnormal taste (38%), blurred taste (35%) to loss of taste (24%), and loss of taste was evidenced to correlate with SARS‐CoV‐2 viral load 6 . Other clinical manifestations of Covid‐19 such as ulcers, vesicles, vesicular bleeding, necrotizing gingivitis, desquamative gingivitis, which have been reported to involve periodontal structures/mucosa remain unclear to be directly associated with SARS‐CoV‐2 infection 5,7–10 . These symptoms are rather ascribed to immune dysfunction associated with SARS‐CoV‐2 infection, superinfection with other microorganisms and disease‐related emotional stress.…”

Section: Periodontal Manifestations In Covid‐19 Patients?mentioning

confidence: 99%

Covid‐19 and SARS‐CoV‐2 infection in periodontology: A narrative review

Droździk

2022

J of Periodontal Research

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The present review examined the available evidence on possible involvement of gingival tissues in SARS‐CoV‐2 infection. Gingival tissue possess SARS‐CoV‐2 entry and transmission factors, among them ACE2 (angiotensin‐converting enzyme 2) and TMPRSS2 (transmembrane protease serine 2), which are the principal mediators of the virus cell invasion. Clinical observations reveal SARS‐CoV‐2 RNA in periodontal tissues and crevicular fluid, suggesting that the periodontium may act as an entry point for the virus and/or as a dissemination site. The preliminary observations prove infection potential of gingival crevicular fluid and shed epithelial cells from the periodontium. There are also findings on potential associations between periodontitis and Covid‐19 (coronavirus disease 2019). PubMed and Scopus databases were used to search for suitable keywords such as: SARS‐CoV‐2, Covid‐19, oral virus infection, gingival crevicular fluid, oral mucosa, periodontium, gingiva, ACE2, TMPRSS2, Furin, diagnosis, topical treatment, vaccine and the related words for relevant publications. Data extraction and quality valuation of articles were performed by the author. The review addressed seven major domains: periodontal structures as SARS‐CoV‐2 infection site, the periodontal changes under SARS‐CoV‐2 infection, potential associations between periodontitis and Covid‐19, periodontal oral care in Covid‐19, crevicular fluid as potential transmission factor and preventive measures. The search process in PubMed and Scopus was updated up to 31 March 2022. Finally 68 articles were retrieved for the final analysis, from the initial database searches. According to the inclusion criteria articles in English language without any date restriction were included. The included studies were mostly original articles, and published in 2020 and 2021 with the aim to describe Covid‐19 and SARS‐CoV‐2 infection in periodontology. As a conclusion it can be stated that gingival tissues may play a role in SARS‐CoV‐2 infection.

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Oral manifestations associated with COVID-19 disease: An observational cross sectional study

Cited by 14 publications

References 23 publications

The Retrospective Pilot Study of the Prevalence of Olfactory Dysfunction or Loss of Smell, Loss of Taste and Oral Manifestations among COVID-19 Positive Health Workers in Muscat, Oman

The Retrospective Pilot Study of the Prevalence of Olfactory Dysfunction or Loss of Smell, Loss of Taste and Oral Manifestations among COVID-19 Positive Health Workers in Muscat, Oman

Sergančiųjų Covid-19 Burnos Pakitimų Ypatumai

Covid‐19 and SARS‐CoV‐2 infection in periodontology: A narrative review

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