2011
DOI: 10.1007/s12105-010-0237-8
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Oral Manifestations of Dermatologic Disease: A Focus on Lichenoid Lesions

Abstract: Lichenoid changes in the oral mucosa can be encountered in a wide range of lesions with varied etiologies including immune-mediated disorders, reactions to systemic medications and to dental materials. Dysplasia of the oral cavity can exhibit a lichenoid histology, which may mask the potentially cancerous component. Another unusual clinical disease, proliferative verrucous leukoplakia, can often mimic oral lichen planus clinically requiring careful correlation of the clinical and pathologic features.

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Cited by 45 publications
(41 citation statements)
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“…Lichen planus is an immune mediated T-cell response with an approximated prevalence of 0.22 to 5% and most frequently affecting middle aged women and typically affecting the buccal mucosa, tongue, lips, gingiva [ 14 ].…”
Section: Discussionmentioning
confidence: 99%
“…Lichen planus is an immune mediated T-cell response with an approximated prevalence of 0.22 to 5% and most frequently affecting middle aged women and typically affecting the buccal mucosa, tongue, lips, gingiva [ 14 ].…”
Section: Discussionmentioning
confidence: 99%
“…“Lichenoid” is a term frequently used in anatomopathological reports that could condition the clinical diagnosis. The description of a juxtaepithelial lymphocytic‐infiltrate band (JLIB) associated with ED, OSCC, and VC highlights that these histological findings are not specific for OLP/OLL 23‐25 . Histopathological features of OLP include JLIB that is confined to the superficial part of the connective tissue, signs of hydropical degeneration of the basal and/or suprabasal cell layers with keratinocyte apoptosis and hyperkeratosis 1 .…”
Section: Discussionmentioning
confidence: 99%
“…This is rarely the case and, as drug reactions can develop in patients who have been taking a drug for many years. 27 As patients are often on several medications, and drug reactions may take several months to resolve, 28 The disease has two main forms: systemic lupus erythematosus (SLE) which affects many organs, and the more benign cutaneous lupus erythematosus (CLE) which is limited to the skin and mucosae. [29][30][31] The clinical picture will vary from patient to patient, but SLE can affect the skin (malar or butterfly rash and disc-shaped, photo sensitive erythematous plaques), mouth (ulceration and red and white patches similar to those in lichen planus), joints (non-erosive arthritis affecting two or more joints), kidneys (proteinuria), nervous system (seizures or psychosis) and also cause cardiac and haematological disturbance (anaemia, leukopenia, thrombocytopaenia).…”
Section: Lichenoid Drug Reactionsmentioning
confidence: 99%