Oral manifestations of secondary hyperparathyroidism: A case report

Kakade, Sunita P; Gogri, Ajas A; Umarji, Hemant R; Kadam, Sonali

doi:10.4103/0976-237x.169840

Cited by 18 publications

(15 citation statements)

References 8 publications

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“…3,12 OF/RO usually affects the long bones, ribs, and pelvis, 6 whereas jaw bone involvement is a very rare manifestation of the disease. 12,22 There is no significant sex predilection, and adult patients are the most affected, although our study found a female prevalence (female-tomale ratio 1.66:1) and a 12 year old affected by the lesion. The pathologic process often involves the jaws diffusely, as illustrated in 3 of our reports, possibly leading to severe facial asymmetries and disfigurement.…”

Section: Discussioncontrasting

confidence: 58%

Oral and maxillofacial manifestations of chronic kidney disease–mineral and bone disorder: a multicenter retrospective study

Pontes

Lopes

Souza

et al. 2018

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Section: Discussioncontrasting

confidence: 58%

Oral and maxillofacial manifestations of chronic kidney disease–mineral and bone disorder: a multicenter retrospective study

Pontes

Lopes

Souza

et al. 2018

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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“…16 Furthermore, Kakade et al in 2015 reported a case of ROD in a patient with secondary HPT. 4 Radiographic findings of all cases demonstrated similar clinical and radiographic features such as ground-grass appearance, loss of trabecular pattern, and diffuse swelling of the maxilla and mandible. However, the majority of cases of severe jaw enlargement associated with HPT failed to return to normal contours even after renal transplantation.…”

Section: Case Reportmentioning

confidence: 69%

“…It can occur as a complication of CRF as a result of ROD. [4][5][6][7][8][9][10][11] ROD is a frequent long-term complication of renal disease that can induce a broad spectrum of bone metabolism disorders associated with different pathogenic pathways. The symptoms of ROD comprise bone demineralization with trabeculation and cortical loss, giant cell radiotransparencies, or metastatic calcifications of the soft tissues.…”

Section: Case Reportmentioning

confidence: 99%

“…The risk of bone fracture and obstruction of airways due to deformation of the hard palate are the important issues that require concern during dental treatment. [4][5][6]12 This patient was diagnosed with SLE and treated with systemic corticosteroids for 13 years. Long-term treatment of this disease induced renal inflammation that later developed into CRD and CRF.…”

Section: Case Reportmentioning

confidence: 99%

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Oral Manifestations of Renal Osteodystrophy in a Patient with Systemic Lupus Erythematosus with Chronic Renal Failure and Systemic Lupus Erythematosus with Chronic Renal Failure and Secondary Hyperparathyroidism: A Case Report Secondary Hyperparathyroidism: A Case Rep

Riyachan¹,

Subarnbhesaj²,

Sarideechaigu³

et al. 2019

J Dent Indones

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Systemic lupus erythematosus (SLE) is one of the chronic autoimmune diseases that leads to multiple manifestations in several organ systems, including chronic renal failure (CRF). Renal osteodystrophy (ROD) is one of the most common complications of CRF associated with secondary hyperparathyroidism (HPT). A combination of CRF and HPT can result in broad-spectrum disorders in the metabolism of minerals such as calcium, phosphorus, and vitamin D, which can affect bone turnover, mineralization, and volume. Radiographic alterations of ROD are considered as one of the earliest signs of CRF. Objective: To describe the oral manifestations in both the maxilla and mandible of a patient with ROD resulting from SLE with CRF and secondary HPT. Case report: A 37-yearold female patient visited the Faculty of Dentistry, Khon Kaen University, for the management of traumatic ulcers on the left and right buccal mucosa and generalized maxillary and mandibular bony hard swellings with mild paresthesia in the lower left mandible for a period of 4 months. The patient had been suffering from SLE for approximately 20 years. However, secondary HPT and CRF as consequences of refractory SLE were being treated concomitantly. Intraoral examination showed several nonpainful ulcers on the left and right buccal mucosa. Radiographic findings revealed generalized loss of lamina dura with thinning of cortical outlines of the maxilla and mandible. Due to complications associated with treatment and the general conditions of this patient, she was referred for treatment to a palliative care unit. Conclusion: Systemic symptoms and complications of patient with ROD with CRF and secondary HPT are seriously problematic. The role of the dentist in this case is to detect the disease, lessen the complications, and make the patient experience minimal pain and side effects in palliative care.How to cite this article: Riyachan I, Subarnbhesaj A, Sarideechaigul W, Klanrit P. Oral manifestations of renal osteodystrophy in a patient with systemic lupus erythematosus with chronic renal failure and secondary hyperparathyroidism: a case report. J Dent Indones. 2019;26(3):165-169.

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“…PTH level increases when the serum calcium concentration is low, such as when calcium intake is lacking or when very low vitamin D levels inhibit sufficient enteral calcium uptake, and in the case of chronic kidney disease. 1,2 In general, PTH attempts to elevate serum calcium levels by stimulating renal calcium reuptake, enteral calcium uptake, and bony calcium release. The effects of PTH can vary according to the age of the patient, the serum PTH concentration pattern, and the skeletal site.…”

mentioning

confidence: 99%

Secondary hyperparathyroidism causing increased jaw bone density and mandibular pain: a case report

Aerden

Grisar

Nys

et al. 2018

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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We present the case of a 32-year-old male patient complaining of recurrent mandibular pain for 3.5 years. Panoramic radiography indicated increased cortical density of the mandibular lower border. Scintigraphy and single-photon emission computed tomography revealed metabolic hyperactivity in that region without pathologic lymph nodes. A bone biopsy specimen of the mandibular lower border did not have inflammation or cytologic atypia. Endocrinologic investigation confirmed secondary hyperparathyroidism as a result of hypovitaminosis D. Several weeks after starting therapy with oral vitamin D supplements, the symptoms completely disappeared. Increased cortical density is a rare manifestation of secondary hyperparathyroidism, which normally causes the lamina dura to vanish and produces a ground-glass appearance as a result of blurring of the trabecular bone pattern. Because focal hyperostosis can have multiple benign or malignant causes, radiologic examination of the jaw bones is indispensable for evaluating orofacial pain. Increased cortical density may be caused by metabolic diseases, requiring further investigations, including biopsy and blood analysis.

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Oral manifestations of secondary hyperparathyroidism: A case report

Cited by 18 publications

References 8 publications

Oral and maxillofacial manifestations of chronic kidney disease–mineral and bone disorder: a multicenter retrospective study

Oral and maxillofacial manifestations of chronic kidney disease–mineral and bone disorder: a multicenter retrospective study

Oral Manifestations of Renal Osteodystrophy in a Patient with Systemic Lupus Erythematosus with Chronic Renal Failure and Systemic Lupus Erythematosus with Chronic Renal Failure and Secondary Hyperparathyroidism: A Case Report Secondary Hyperparathyroidism: A Case Rep

Secondary hyperparathyroidism causing increased jaw bone density and mandibular pain: a case report

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