“…Dentally, there is a demineralization of the teeth, progressive periodontal disease, and mucositis [1-4, 9-11, 16, 18]. As the disease progresses, other than dry oral mucosa and saliva thickening, there have been reports of mouth burning, pain, depression, irritability and sleep alterations [1,4,5,9,11,12,[14][15][16][17].…”