Oral Mesotherapy: Might Be Considered as An Adjunctive Technique for the Different Surgical Procedures?

Yussif, Nermin

doi:10.5772/intechopen.88355

Cited by 3 publications

(2 citation statements)

References 56 publications

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“…Some preliminary data indicate that mesotherapy technique could also be applied to oral mucosa. 30 Applications in the dental field for both therapeutic and cosmetic purposes must be carefully tested before being proposed for routine clinical practice.…”

Section: Dermal Pharmacodynamics In the Management Of Other Diseasesmentioning

confidence: 99%

A Call to Action by the Italian Mesotherapy Society on Scientific Research

Mammucari¹,

Paolucci²,

Russo³

et al. 2021

DDDT

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Mesotherapy (local intradermal therapy, LIT) is a technique used to slowly spread drugs in tissues underlying the site of injection to prolong the pharmacological effect with respect to intramuscular injection. Recommendations for proper medical use of this technique have been made for pain medicine and rehabilitation, chronic venous disease, sport medicine, musculoskeletal disorders, several dermatological conditions, skin ageing, and immune-prophylaxis. Although mesotherapy is considered a valid technique, unresolved questions remain, which should be answered to standardize methodology and dosing regimen as well as to define the right indications in clinical practice. New randomized controlled trials are needed to test single products (dose, frequency of administration, efficacy and safety). Even infiltration of substances for dermo-cosmetic purposes must be guided by safety and efficacy tests before being proposed by mesotherapy. In this article, we put forth a preclinical and clinical research plan and a health technology assessment as a call to action by doctors, researchers and scientific societies to aid national health authorities in considering mesotherapy for prevention, treatment and rehabilitation paths.

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Section: Dermal Pharmacodynamics In the Management Of Other Diseasesmentioning

confidence: 99%

A Call to Action by the Italian Mesotherapy Society on Scientific Research

Mammucari¹,

Paolucci²,

Russo³

et al. 2021

DDDT

View full text Add to dashboard Cite

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“…The original mesotherapy technique introduced by Pistor in dermatology [7] has undergone modifications as pioneered by Yussif et al, leading to innovations such as oral mesotherapy [8]. This method involves the administration of therapeutic agents into the intraepithelial layers of oral tissue with fine needles [9].…”

Section: Introductionmentioning

confidence: 99%

A Minimally Invasive Technique for the Management of Physiologic Gingival Melanin Hyperpigmentation: A Case Series

Ravindran,

Muthukumar

et al. 2024

Cureus

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An attractive smile enhances an individual's self-confidence. The overall harmony of a smile can be attributed to the interplay of the teeth's shape, color, and position along with the gingival tissue. Gingival pigmentation is observed across all human races, exhibiting variations from one race to another. Typically, gingival hyperpigmentation results from the abnormal buildup of melanin in the gingival tissue, imparting a dark appearance on the gums. Various procedures, collectively known as gingival depigmentation, are employed to address gingival hyperpigmentation. While the initial outcomes of depigmentation procedures are often promising, one common issue associated with them is the potential for re-pigmentation. This article aims to evaluate the clinical effectiveness and patient-reported outcomes of intraepidermal (oral mesotherapy) vitamin C injection for nonsurgical management of physiologic gingival melanin hyperpigmentation.

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Comparison of Various Minimally Invasive Techniques for the Management of Gingival Hyperpigmentation: A Case Report

Ashokkumar,

Krishnakumar,

Ravindran

et al. 2024

Cureus

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Gingival hyperpigmentation is a condition wherein there is excessive deposition of melanin pigment, which is produced by the melanocytes of the gingiva. Gingival depigmentation is a periodontal surgical procedure whereby the pigmentation is removed or reduced by various surgical techniques that are associated with significant postoperative pain, bleeding, and recurrence. Laser ablation has been recognized as one of the minimally invasive, effective, comfortable, and reliable techniques for gingival depigmentation. The use of lasers has several advantages such as high patient compliance, short healing period, no or very slight pain, and hemorrhage. On the contrary, mesotherapy is a minimally invasive technique that uses fine-gauge needles to locally administer modest amounts of Vitamin C to the mesoderm layer to achieve cosmetic goals. Recently, some case studies have shown that ascorbic acid (Vitamin C) can be used in the management of gingival pigmentation. The objective of this case report is to compare the clinical efficacy of these two techniques for gingival depigmentation and to arrive at an effective minimally invasive alternative for gingival depigmentation.

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Oral Mesotherapy: Might Be Considered as An Adjunctive Technique for the Different Surgical Procedures?

Cited by 3 publications

References 56 publications

A Call to Action by the Italian Mesotherapy Society on Scientific Research

A Call to Action by the Italian Mesotherapy Society on Scientific Research

A Minimally Invasive Technique for the Management of Physiologic Gingival Melanin Hyperpigmentation: A Case Series

Comparison of Various Minimally Invasive Techniques for the Management of Gingival Hyperpigmentation: A Case Report

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