Oral neurovascular hamartoma: a lesion searching for a name

Allon, Irit; Allon, Dror M.; Hirshberg, Avraham; Shlomi, Benjamin; Lifschitz-Mercer, Beatriz; Kaplan, Ilana

doi:10.1111/j.1600-0714.2011.01101.x

Cited by 20 publications

(36 citation statements)

References 26 publications

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“…These nerve bundles are reactive with S-100 protein. This feature can be easily used as a criterion for diagnosis while examining 13. This reactivity was also pivotal in our case to reach the final diagnosis.…”

Section: Discussionmentioning

confidence: 68%

Oral neurovascular hamartoma: an extraordinary verdict in the oral cavity

et al. 2014

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The presence of a neurovascular hamartoma within the oral cavity is truly a rare entity. Scarcely reported in the literature, these hamartomas are smooth, pinkish masses and are painless, and therefore difficult to diagnose. They are benign in nature and apply pressure to their surroundings. The histological diagnosis remains the gold standard as it comprises of neural tissue and vascular components. Treatment is surgical excision with adequate margins. Recurrence is reported in cases of incomplete resection.

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Section: Discussionmentioning

confidence: 68%

Oral neurovascular hamartoma: an extraordinary verdict in the oral cavity

et al. 2014

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“…5 The lesion here is unusual in the sense that it was histopathologically composed of numerous thick and thin-walled mature blood vessels of varying size, along with several well-formed nerve tissue embedded in fibroadipose stroma. These features are similar to NVH as confirmed by morphometric analysis of Allon et al 4 They stated that the two features, which can be used as diagnostic criteria of NVH are presence of several recognizable nerve bundles and nerve bundles grouped in close proximity to blood vessels. 4 Clinically, this case was difficult to distinguish from neurofibromatosis as it also sometimes manifests with massive overhanging masses.…”

Section: Discussionmentioning

confidence: 68%

“…Currently, in literature, no specific and clear diagnostic criteria have been laid down for NVH. 4 The term hamartoma is defined as nonneoplastic malformation characterized by proliferation of mature cells and tissues indigenous to the affected part. 2 However, there is an excess of one or more tissue types in a disorganized manner.…”

Section: Discussionmentioning

confidence: 99%

Neurovascular Hamartoma of Face: An Unusual Clinical Presentation

Fande¹,

Patil²,

Ghatage³

et al. 2017

World Journal of Dentistry

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Introduction: Neurovascular hamartomas (NVH) are relatively uncommon and have been very rarely reported in head and neck region. The rarity could be attributed to it being unrecognized and/or unreported. They constitute unique group of lesions with specific histopathological features.Case report: Authors report a case of 23-year-old male patient with NVH of face with an unusual clinical presentation. Conclusion:Neurovascular hamartoma is a histopathological diagnosis made for small to medium-sized vessels and closely packed groups of well-formed nerve bundles within a loose connective tissue matrix and the inflammatory component is minimal or absent.Clinical significance: Neurovascular hamartomas have specific features, and, therefore, they should not be considered as any reactive lesion or any hamartomatous lesions. Neurovascular hamartomas in fact represents a separate and unique entity.

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“…Hamartoma is defined as a non-neoplastic, uni- or multifocal developmental malformation, comprising a mixture of cytologically normal mature cells and tissues which are indigenous to the anatomic location, exhibiting a disorganized architectural pattern with predominance of one of its components (3–6). Hamartomas may occur in any organ, but are most commonly located in the lungs (7), liver (8), pancreas (9) and spleen (10); however, they are rare in the esophagus.…”

Section: Discussionmentioning

confidence: 99%

Intramural chondroid hamartoma in the distal esophagus in an adult: A case report and review of the literature

Suping

Wei

et al. 2016

Molecular and Clinical Oncology

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Hamartoma of the esophagus is a rare lesion and the number of cases reported in the literature to date is limited. The majority of hamartomas are intraluminal tumors located in the upper third of the esophagus. Histopathologically, the majority of these tumors comprise a mixture of adipose tissue, skeletal/smooth muscle tissue, vascular components and fibrous connective tissue. We herein present the case of a 33-year-old man with an intramural chondroid hamartoma located in the lower third of the esophagus. The patient underwent esophagotomy and the histopathological examination revealed that the tumor was mainly composed of chondroid tissue (60%) admixed with adipose tissue (25%) and fibrous connective tissue (15%). The aim of this study was to describe another variant of esophageal hamartoma, which exhibits a versatile phenotype.

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Oral neurovascular hamartoma: a lesion searching for a name

Abstract: Oral NVH may not be as rare as previously considered. Morphometric analysis demonstrated that NVH presents a separate distinct entity.

Cited by 20 publications

References 26 publications

Oral neurovascular hamartoma: an extraordinary verdict in the oral cavity

Oral neurovascular hamartoma: an extraordinary verdict in the oral cavity

Neurovascular Hamartoma of Face: An Unusual Clinical Presentation

Intramural chondroid hamartoma in the distal esophagus in an adult: A case report and review of the literature

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