“…There are several references in the literature reporting successful treatment of oral verrucous carcinoma. They include: Bleomycin intraarterially, 19 or by local injection 12 ; Methotrexate in low doses or tumoricidal doses 9,20 ; cryotherapy 11,12,21 ; and carbon dioxide laser therapy 22 . Radiation therapy is also an option, although anaplastic transformation has been reported shortly after radiation therapy, 23 other cases have been successfully treated 24…”