Oral pathology in the dental office: survey of 20, 575 biopsy specimens

Bhaskar, Surindar N.

doi:10.14219/jada.archive.1968.0119

Cited by 81 publications

(82 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The present study demonstrated that the overall distribution of lesions analysed in a Brazilian oral pathology laboratory was similar to that observed in other laboratories in the United Kingdom, 11 United States of America [12][13][14] and Brazil. [15][16][17] Most specimens analyzed in this reference oral pathology laboratory were diagnosed over a 10-year period as inflammatory lesions or normal tissue.…”

Section: Discussionsupporting

confidence: 84%

“…[11][12][13][14][15][16][17] Periapical inflammatory lesions and NNPD were the most frequent lesions in this diagnostic category. The frequency of periapical inflammatory lesions was similar to that reported by Jones and Franklin 11 and Baskar, 14 but much higher than that described by Weir et al, 12 Simões et al, 15 Nascimento et al 16 and Volkweis et al 17 This finding may be related to the profile of our sample, in which most patients sought tooth extraction as a treatment for decayed teeth usually associated with periapical inflammatory lesions. Moreover, it is important to emphasize that specimen sources vary considerably among oral pathology laboratories.…”

Section: Discussionmentioning

confidence: 99%

“…1 The literature is vast regarding estimated occurrences of oral lesions such as oral cancer, [2][3][4] as well as odontogenic 5,6 and salivary gland tumors. [7][8][9][10] Contrarily, only few studies have documented the frequency of histologically confirmed lesions in adults, [11][12][13][14] and data are particularly scarce in Brazil. For instance, Simões et al 15 and Nascimento et al 16 evaluated 1,040 and 2,147 specimens, respectively, in studies conducted in oral pathology laboratories located in northeastern Brazil.…”

mentioning

confidence: 99%

See 2 more Smart Citations

A 10-year study of specimens submitted to oral pathology laboratory analysis: lesion occurrence and demographic features

et al. 2012

View full text Add to dashboard Cite

A 10-year study of specimens submitted to oral pathology laboratory analysis: lesion occurrence and demographic features Abstract: The purpose of the present paper was to describe the range of lesions histologically diagnosed in an oral pathology laboratory in southern Brazil. A retrospective study of 8,168 specimen analyses recorded between 1995 and 2004 was conducted. The records were retrieved from the Oral Pathology Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, RS, Brazil. A total of 6,831 valid cases (83.63%) were examined. Of these, inflammatory lesions were the most common occurrences (n = 4,320; 63.24%). Benign and malignant tumors accounted for 7.66% (n = 523) and 1.9% (n = 130) of the occurrences, respectively. Significant associations were observed between nonneoplastic proliferative disorders and benign mesenchymal tumors in females, and between squamous cell carcinoma and leukoplakia in males. Most diagnoses were benign in nature and had an inflammatory etiology. The association of some demographic characteristics with the occurrence of lesions suggests that these characteristics should be considered in performing differential diagnoses.

show abstract

Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

A 10-year study of specimens submitted to oral pathology laboratory analysis: lesion occurrence and demographic features

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Most frequently these masses are reactive, resulting from local irritation or trauma, including fibrous overgrowth, pyogenic granuloma, mucous extravasation and others [2][3][4][5][6][7][8][9]. However, the complete pathological spectrum of mucosal exophytic masses also includes developmental anomalies, infections with various microorganisms, granulomatous inflammatory reactions, cysts and pseudo-cysts, malformations, hamartoma, as well as benign and malignant neoplasia [1,10,11].…”

Section: Introductionmentioning

confidence: 99%

“…Although the presence of surface ulceration in an exophytic mucosal mass is not pathognomonic for any specific condition, ulcerated masses are conventionally treated with a higher degree of suspicion for malignancy than non-ulcerated mucosal masses. A search of the English literature yielded several studies analyzing the prevalence of oral lesions based on either clinical or of pathologic findings [2][3][4][5][6][7][8][9][14][15][16][17][18], but studies relating specifically to the significance of surface ulcerations as an indicator for malignancy in mucosal exophytic lesions were not found.…”

Section: Introductionmentioning

confidence: 99%

The Significance of Surface Ulceration as a Sign of Malignancy in Exophytic Oral Mucosal Lesions: Myth or Fact?

Allon¹,

Allon²,

Anavi³

et al. 2012

Head and Neck Pathol

View full text Add to dashboard Cite

To compare the spectrum of pathologies in ulcerated versus non-ulcerated exophytic oral mucosal lesions and explore the significance of surface ulceration as an indication of malignancy. Retrospective analysis of exophytic lesions of the oral mucosa, 2009-2011. 713 biopsies of exophytic lesions of oral mucosa were included, of which 9.4 % were ulcerated. Significant differences were found between ulcerated and non-ulcerated lesions. Of the ulcerated lesions 67.2 % were reactive, 31.3 % malignant and 1.5 % benign, compared to 86, 8.4 and 5.6 % respectively in non-ulcerated lesions (p \ 0.0001). Malignancies were most prevalent in ulcerated lesions, in patients over 50. Malignancies presented the highest ulceration rate (36.8 %, p \ 0.001), compared to reactive (7.5 %) and benign neoplasia (1.8 %), however, the majority of oral mucosal malignancies (63.2 %) presented as non-ulcerated masses. Squamous cell carcinoma presented the highest ulceration rate among malignancies, but even these were only ulcerated in 50 % of cases. Nonepithelial malignancies were non-ulcerated in all cases. One-third of all malignancies were not suspected as such clinically, however, there was a better agreement between the clinical and microscopic diagnosis of malignancy in ulcerated lesions. Although the statistical likelihood of ulcerated masses to represent malignancy was higher than non-ulcerated lesions, especially in patients over 50, the majority of malignancies presented as non-ulcerated masses. Thus, all exophytic lesions should be submitted for microscopic analysis, and the status of ulceration should not be regarded neither as a factor in the decision to biopsy, nor a reliable indicator for malignancy.

show abstract

Oral pathology in the dental office: survey of 20, 575 biopsy specimens

Cited by 81 publications

References 1 publication

A 10-year study of specimens submitted to oral pathology laboratory analysis: lesion occurrence and demographic features

A 10-year study of specimens submitted to oral pathology laboratory analysis: lesion occurrence and demographic features

The Significance of Surface Ulceration as a Sign of Malignancy in Exophytic Oral Mucosal Lesions: Myth or Fact?

Suggested Reading

Contact Info

Product

Resources

About