Oral phaeohyphomycosis: Figure 1

Cardoso, Sérgio Vitorino; Campolina, Sabrina S.; Guimarães, André Luiz Sena; Faria, Paulo Rogério de; Costa, E M da C; Gomez, Ricardo Santiago; Rocha, A; Caligiorne, Rachel Basques; Loyola, Adriano Mota

doi:10.1136/jcp.2005.035808

Cited by 10 publications

(14 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An unspeciated organism of the genus Alternaria was reported to cause a single, oral, nodular lesion in an affected human. 26 In the present case, the oral lesions were, perhaps, macroscopically more comparable with the lesions described in candidiasis of humans 27 and, more rarely, dogs. 28 However, material from the lip and tongue lesions failed to yield fungal elements on culture and, as biopsy would have required general anaesthesia, this was not carried out on this compromised patient.…”

Section: Discussionsupporting

confidence: 84%

See 1 more Smart Citation

Cutaneous Alternaria infectoria infection in a dog in association with therapeutic immunosuppression for the management of immune‐mediated haemolytic anaemia

Dedola

Stuart

Ridyard

et al. 2010

Veterinary Dermatology

View full text Add to dashboard Cite

A 4-year-old, ovariohysterectomized, English springer spaniel on immunosuppressive therapy was re-examined for the review of its immune-mediated haemolytic anaemia and the recent development of skin lesions. For the 3 months since hospital discharge, the dog had been receiving 1.3 mg/kg prednisolone and 2.6 mg/kg ciclosporin, both administered orally twice daily. Physical examination revealed hepatomegaly and multiple, purulent, crusting, erosive to ulcerative lesions over different body areas. Onychorrhexis had occurred on one digit and the underlying corium had blackened. There were two proliferative and one plaque-like lesions in the mouth. Thick walled fungal hyphae were detected in impression smears from all skin lesions and staining with periodic acid-Schiff's stain confirmed the presence of multiple fungal hyphae and spores in all biopsies examined. Fungal culture isolated a heavy, pure growth of an Alternaria sp. which was identified as A. infectoria by sequencing the internal transcribed spacer 1 region of the rRNA gene. The animal's condition prevented detailed investigation of the oral lesions. Withdrawal of the ciclosporin and reduction of the prednisolone dosage resulted in spontaneous resolution of the skin lesions within 40 days. Further gradual decrements in the prednisolone dosage to zero were carried out without recurrence of the immune-mediated haemolytic anaemia. After 12 months, there has been no recurrence of either the skin lesions or the anaemia. To the authors' knowledge, this is the first reported case of A. infectoria infection in a dog.

show abstract

Section: Discussionsupporting

confidence: 84%

“…An unspeciated organism of the genus Alternaria was reported to cause a single, oral, nodular lesion in an affected human 26 . In the present case, the oral lesions were, perhaps, macroscopically more comparable with the lesions described in candidiasis of humans 27 and, more rarely, dogs 28 .…”

Section: Discussionsupporting

confidence: 71%

Cutaneous Alternaria infectoria infection in a dog in association with therapeutic immunosuppression for the management of immune‐mediated haemolytic anaemia

Dedola

Stuart

Ridyard

et al. 2010

Veterinary Dermatology

View full text Add to dashboard Cite

show abstract

“…It could be interpreted as an additional evidence for a traumatic route of infection, as this population has been anecdotally quoted to chew vegetable residues and to use plant fragments as toothpicks. We have recently observed a case of another rare oral mycosis that could be explained by local inoculation 30 . Others have made similar observations, 31–33 and experimental works have suggested that laminin in the basal lamina of the oral mucosa could favour installation of P. brasiliensis , possibly through adhesion‐mediated gp43 34 .…”

Section: Discussionmentioning

confidence: 62%

“…We have recently observed a case of another rare oral mycosis that could be explained by local inoculation. 30 Others have made similar observations, [31][32][33] and experimental works have suggested that laminin in the basal lamina of the oral mucosa could favour installation of P. brasiliensis, possibly through adhesion-mediated gp43. 34 Oral mucosal infection by direct inoculation has been critically questioned in a recent experimental study.…”

Section: Discussionmentioning

confidence: 68%

Paracoccidioidomycosis: a series of 66 patients with oral lesions from an endemic area

Brazão–Silva

Andrade

Franco

et al. 2010

Mycoses

View full text Add to dashboard Cite

Paracoccidioidomycosis (PCM) is the most important systemic mycosis in Latin America. It has been regarded as a multifocal disease, with oral lesions as the prominent feature. To provide useful information concerning the diagnosis and management of the disease, this study describes demographic and clinical data from the medical records of a consecutive series of 66 Brazilian patients from an endemic area, evaluated in a referral centre for oral diagnosis. In this sample of patients, there was a predominance of middle-aged male patients, who were primarily rural workers. Chronic multifocal disease was prevalent, with lesions also detected in the lungs, lymph nodes, skin or adrenal glands. Most of the cases presented with lesions at the gingival mucosa followed by the palate and lips; these conditions occurring in the oral cavity were frequently associated with pain. Importantly, most of the patients sought professional care for oral lesions. The diagnosis was obtained through exfoliative cytology and/or biopsy of the oral lesions. Medical treatment was effective, and there were no mortalities in the sample. The present findings not only confirm the importance of oral lesions in the diagnosis and management of PCM but also illustrate that questions still remain unclear, such as the possibility of direct inoculation of the fungus onto oral tissues.

show abstract

“…While subcutaneous infections by dematiaceous fungi secondary to traumatic implantation have been described in human subjects, intraoral infection by these microorganisms has been previously reported in at least two cases, one involving the lower labial mucosa [5] and the other infecting a third molar extraction socket [6]. We present a case of oral phaeohyphomycosis within an epitheliumlined cyst of the anterior midline hard palate.…”

Section: Introductionmentioning

confidence: 86%

Intraoral Phaeohyphomycosis

Rawal

Kalmar

2012

Head and Neck Pathol

View full text Add to dashboard Cite

Phaeohyphomycosis is an infection caused by pigment-producing saprophytic fungi. Systemic infections may occur in the immunocompromised patient. Infection in healthy individuals may result in subcutaneous abscess formation. Oral lesions appear to be rare. A case of intraoral phaeohyphomycosis presenting as a well-demarcated, painful nodule of the anterior hard palate in a 12-year-old healthy male is described. The mass was excised and the diagnosis was established following histopathologic examination of the tissue.

show abstract

Oral phaeohyphomycosis: Figure 1

Cited by 10 publications

References 10 publications

Cutaneous Alternaria infectoria infection in a dog in association with therapeutic immunosuppression for the management of immune‐mediated haemolytic anaemia

Cutaneous Alternaria infectoria infection in a dog in association with therapeutic immunosuppression for the management of immune‐mediated haemolytic anaemia

Paracoccidioidomycosis: a series of 66 patients with oral lesions from an endemic area

Intraoral Phaeohyphomycosis

Contact Info

Product

Resources

About