Oral Phenazopyridine HCL for Ureter Orifice Identification and Retrograde Stenting

Abstract

Objective: To compare the successful of the identification of the ureteral orifice at cervical cancer patients who received phenazopyridine orally and to analyze the correlation between hydronephrosis and successful rate for retrograde stenting. Material & Method: This was a comparative experimental study, using phenazopyridine hcl orally prior to cystoscopy to identify the ureteral orifice on cervical cancer patients and to perform retrograde stenting on spotted ureteral orifice. Forty samples provided consent to enroll in this study. Mean age was 49.2 ± 5.16 years. Thirty-four out of 40 samples was confirmed as squamous cell carcinoma type. Results: Chi-square test demonstrated no significant differentiation in finding ureteral orifice between treatment and control group on stage 3B (p = 0.408). However, result shown conversely on stage 4A (p = 0.046). There was no significant disparity in conducting retrograde stenting between treatment and control group on stage 2B and 3B (p = 0.221 and p = 0.197). There was no significant correlation between hydronephrosis gradation and retrograde stenting on control group (p = 0.144). Conclusion: Administration of phenazopyridine HCL orally in cervical cancer patients increase success for ureteral orifice identification and retrograde stenting, but not statistically significant. There is no correlation between hydronephrosis with a success retrograde stenting.Keywords: Cervical cancer, hydronephrosis, phenazopyridine hcl, ureteral orifice, retrograde stenting.

Charateristics of Gynecological Abnormalities and Types of Urine Diversion at Dr Soetomo Hospital, Surabaya, Indonesia, in Three-Year Period

“…(Hewitson 2009). Whereas, Gumilar et al (2012) stated that there was no relationship between the gradation of hydronephrosis and the success rate of retrograde DJ stent placement in patients with uterine cervical carcinoma.…”

“…Failure of DJ stents in ureteric obstruction due to malignancy is also quite high in ureteral distal distal obstruction when compared to proximal or renal pelvic level obstruction (Kouba et al 2008). Gumilar et al stated that there was no relationship between the gradation of hydronephrosis and the success rate of retrograde DJ stent placement in patients with uterine cervical carcinoma (Gumilar et al 2012).…”

Charateristics of Gynecological Abnormalities and Types of Urine Diversion at Dr Soetomo Hospital, Surabaya, Indonesia, in Three-Year Period

“…The ureteral estuary was not identified when cystoscopy plays a role in 77% of the failure of DJ stent installation in malignant ureteral obstruction (MUO) (Hewitson 2009). Whereas, Gumilar et al (2012) stated that there was no relationship between the gradation of hydronephrosis and the success rate of retrograde DJ stent placement in patients with uterine cervical carcinoma.…”