Oral plasmablastic lymphoma: a case report

Hewson, I

doi:10.1111/j.1834-7819.2011.01348.x

Cited by 5 publications

(2 citation statements)

References 6 publications

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“…The clinical appearance may mimic periodontal disease, Kaposi sarcoma, or melanoma [6]. Radiographic changes include widening of the periodontal ligament space and loss of the lamina dura [7]. …”

Section: Introductionmentioning

confidence: 99%

Plasmablastic Lymphoma of Gingiva Mimicking a Reactive Lesion: A Case Report

Bagul

Mamatha

Mahalle

2012

Case Reports in Dentistry

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Oral plasmablastic lymphoma (PBL) is a rare malignancy, associated with HIV or other immunocompromised conditions. The lesion constituted a new subtype of diffuse large B-cell lymphoma and proposed a distinct entity based on its basic morphology, its clinical behaviour involving predominantly extramedullary sites (particularly oral cavity), and its limited antigenic phenotype data suggesting plasmacytic differentiation. Authors here report a case of apparently healthy individual aged 35 years, presenting one-month history of swelling associated with loosened teeth around upper anteriors. Following incisional biopsy, routine histopathologic and immunohistochemical studies, the diagnosis of plasmablastic lymphoma was given.

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Section: Introductionmentioning

confidence: 99%

Plasmablastic Lymphoma of Gingiva Mimicking a Reactive Lesion: A Case Report

Bagul

Mamatha

Mahalle

2012

Case Reports in Dentistry

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“…Sixty-five papers were identified and further evaluated to include only those reports containing adequate clinical description and histopathological confirmation of the diagnosis; a total of 51 reports describing 55 cases were included for further analyses 7–57…”

Section: Discussionmentioning

confidence: 99%

Unusual cause of tooth mobility

et al. 2020

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We describe a case of a 71-year-old otherwise healthy man who presented to the dental clinic with the chief complaint of mobility involving his upper left molar teeth. The patient was a febrile, and clinical oral examination revealed localised grade II mobility and absence of gingival swelling, erythema or sinus tract. Orthopantogram revealed a poorly defined radiolucency involving the upper left second and third molar teeth. Surgical exploration of the involved area was performed and revealed the presence of a ‘jelly like’ brown tissue that fragments easily. Pathological examination confirmed the diagnosis of diffuse large B cell lymphoma.

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Oral plasmablastic lymphoma in HIV‐infected individuals—A systematic review

Sundararajan,

Bose,

Dineshkumar

et al. 2024

Oral Science International

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Plasmablastic lymphoma (PBL) is an uncommon and aggressive large B‐cell lymphoma that affects immunocompromised individuals. The orofacial region is the most commonly affected site. The primary aim of the article was to review systematically, the cases of oral PBL and consolidate their clinic‐pathological, and molecular characteristics, rehabilitation, and outcome in Human immunodeficiency virus (HIV)‐infected individuals. An electronic literature search was done and 28 articles with a total of 32 cases, of which 27 patients were adults and 5 were pediatrics were included in the review based on the inclusion criteria. Oral PBL was found to be common in HIV‐affected males, frequently involving the gingiva. Histopathology revealed monomorphic neoplastic atypical cells with plasmablastic features and cohesive growth patterns. Immunohistochemistry revealed strong positivity for CD138, and CD 79a. The prognosis of oral PBL in patients with HIV was poor in both adult and pediatric age groups, however, pediatric age groups showed a worse prognosis. Hence, it is crucial to correctly diagnose oral PBL, surgically treat the patients along with chemotherapy and/or radiation therapy, and start ART in HIV‐positive individuals.

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Oral plasmablastic lymphoma: a case report

Cited by 5 publications

References 6 publications

Plasmablastic Lymphoma of Gingiva Mimicking a Reactive Lesion: A Case Report

Plasmablastic Lymphoma of Gingiva Mimicking a Reactive Lesion: A Case Report

Unusual cause of tooth mobility

Oral plasmablastic lymphoma in HIV‐infected individuals—A systematic review

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