Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment

Götz, Carolin; Reinhart, E.; Wolff, Klaus‐Dietrich; Kolk, Andreas

doi:10.1016/j.jcms.2015.08.002

Cited by 6 publications

(6 citation statements)

References 44 publications

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“…In this study, the patients had an average age of 46.1 years and 61.5% of this population were men, which is comparable to those of other studies in this field [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. The fact that a very similar mean age and mean gender was encountered is a factor favouring the quality of the population.…”

Section: Discussionsupporting

confidence: 85%

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Is there need for technical investigations in order to predict potential length of hospital stay of oral infections?

Smeets

Gemels

Groeneveldt

et al. 2019

The American Journal of Emergency Medicine

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Based on the statistical analysis of this population, the research group concludes that a thorough anamnesis and clinical examination should be accompanied by a blood analysis of CRP and white blood cell counts. Only then can a well-founded decision be reached on the severity of the case and the need for hospital admission. In an acute setting, radiological imaging is not required for assessing future morbidity, but it should be performed when accessible.

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Section: Discussionsupporting

confidence: 85%

“…However, 73.44% of the 64 patients received metronidazole, in addition to standard therapy with amoxicillin clavulanic acid or clindamycin. The current literature did not support this combination for treating a generally healthy population of patients with oral infections and abscesses [2,18].…”

Section: Discussionmentioning

confidence: 69%

Is there need for technical investigations in order to predict potential length of hospital stay of oral infections?

Smeets

Gemels

Groeneveldt

et al. 2019

The American Journal of Emergency Medicine

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show abstract

“…In this study, other etiologies were also included, such as postoperative infections, infected cystic lesions and skin infections, since they are also frequent clinical situations in emergency services and can progress to a severe stage if not treated correctly 6,7,18,19 . Another limitation of some studies is the inclusion of patients who were followed up only during hospitalization 20 . Our study evaluated inpatients and outpatients.…”

Section: Discussionmentioning

confidence: 99%

Microbiological profile and antibiotic sensitivity of maxillofacial infections in an emergency hospital

Paula,

Zancopé

2024

Braz. J. Oral Sci.

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Aim: To investigate the bacteriological profile of oral and maxillofacial infections and the pattern of sensitivity to a specific group of antibiotics in a reference emergency hospital in Brazil. Methods: This is a prospective cohort institutional study that studied patients affected by oral and/ or maxillofacial infections in a Brazilian emergency hospital, over a 12-month period, of different etiologies, through data collection, culture and antibiogram tests, and monitoring of the process of resolution of the infectious condition. The variables were analyzed using the chi-square and Mann-Whitney tests, using a significance level of 5%. Results: The sample consisted of 61 patients, 62.3% male. The mean age of participants was 34.3 years. Odontogenic infection was the most frequent etiology and the submandibular space was the most affected. The bacterial species Streptococcus viridans was isolated in 21.6% of cases. Levofloxacin, vancomycin and penicillin were the antibiotics with the highest frequency of bacterial sensitivity, while clindamycin and erythromycin showed the highest percentages of resistance. Conclusions: The results suggest that, among the most used antibiotics for the treatment of these infections, penicillin remains an excellent option of choice for empirical therapy.

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“…The study found a significant percentage of clindamycin-resistant strains (85.9% resistant strains), compared with amoxicillin (43.7% resistant strains) and amoxicillin with clavulanic acid (12% resistant strains) [ 18 ]. Götz et al [ 19 ] investigated the microbiota and its drug susceptibility in purulent facial soft tissue infections requiring extra- or intraoral incision. As in the present study, the cultured microbiota consisted predominantly of the Gram-positive bacteria and viridans group streptococci ( Streptococcus viridans ) that constitute the natural oral microbiota.…”

Section: Discussionmentioning

confidence: 99%

Status of Microbiota in Odontogenic Inflammatory Lesions and Dental Surgery Procedures Performed on an Outpatient Basis

Morawiec

Śmieszek-Wilczewska²,

Bogacz³

et al. 2022

Antibiotics

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Inflammations of the facial part of the skull are most commonly caused by a bacterial infection. They are a frequently occurring pathological process, which results from a rich bacterial flora of the oral cavity, as well as diseased teeth and periodontal tissues. These inflammations have a primarily mixed character with the prevalence of anaerobic bacteria. Gangrene of the dental pulp is the most common odontogenic cause. In the case of inflammations of oral tissues an early and corrective treatment results in quick recovery. The purpose of this work was to assess the efficiency of empirical antibiotic therapy applied in patients with inflammations of oral tissues on the basis of a drug susceptibility profile of bacteria isolated from material extracted from inflammatory lesions. The research material consisted of smears collected from patients with existing acute inflammations in the oral cavity. The smear was collected from the bottom of the lesion after its prior surgical treatment and pus evacuation, and again, 7 days after surgery. In patients with acute odontogenic inflammations the recommended first-line therapy are extended-spectrum penicillins, characterized by a low risk of side effects and strong antimicrobial activity. In the study group, both clindamycin and amoxicillin exhibited high efficiency in treating acute odontogenic inflammatory lesions in the oral cavity.

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Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment

Cited by 6 publications

References 44 publications

Is there need for technical investigations in order to predict potential length of hospital stay of oral infections?

Is there need for technical investigations in order to predict potential length of hospital stay of oral infections?

Microbiological profile and antibiotic sensitivity of maxillofacial infections in an emergency hospital

Status of Microbiota in Odontogenic Inflammatory Lesions and Dental Surgery Procedures Performed on an Outpatient Basis

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