Oral squamous cell carcinoma: A 5 years institutional study

Abstract

Background: Oral squamous cell carcinoma (OSCC) is a major contributor to disability and death caused by malignant tumors. While of global relevance, variations in social, cultural, and geographic factors affect tumor behavior and response to treatment. In this study, we undertake a 5 years institutional review and analysis of OSCC cases in the south Indian setting. Results: The total number of the patients included 65 males (44.8%) and 80 females (55.2%) whose age ranged from 23 to 80 years (mean ± standard deviation; 52.86 ± 13.18 years). An incidence was highest in 40-45 and 60-65 age group. Buccal mucosa 44 (30.4%) was the most common site, followed by tongue 27 (18.6%). Most lesions (58%) were well differentiated. Patients with poorly differentiated lesions had a comparatively lower mean age than their counterparts with other histological varieties, and this was statistically significant (P < 0.05). Conclusion:The pattern of OSCC differs from that of previous studies in relation to incidence and age correlation with the grade of carcinoma. Since the majority of the lesions were well differentiated, there is a need for intensive oral health awareness to encourage early presentation, to cancer center, as this will further enhance prognosis.

A Clinico-Pathological Study of Squamous Cell Carcinoma of Gingivobuccal Complex in Punjab

“…In this study, the mean age of the patients at presentation was 52.53 years. Study is comparable with study of Nayak et al [14] and Lekawale et al [15] From these studies, it is found that most of the SCCs of oral cancer patients present at fifth decade of age. In this study male-to-female ratio was 5:1, which is comparable with that in studies conducted by Iype et al [6] and Dewan et al [16] In this study, the incidence of SCC of the gingivobuccal complex was recorded to be maximum in businessmen (23.33%) followed by housewives and labourers (13.33% each).…”