Oral Squamous Cell Carcinoma Associated With Symphyseal Dental Implants

Gallego, Lorena; Junquera, Luís; Baladrón, J.; Villarreal, Pedro

doi:10.14219/jada.archive.2008.0308

Cited by 49 publications

(68 citation statements)

References 8 publications

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“…However, a direct cause-effect relation between the metal and sarcomatous degeneration in patients has not been demonstrated to date (Black, 1988b;Brown et al, 1987;Case et al, 1996;Goodfellow, 1992). As regards titanium specifically, there are reports of neoplasia in association with dental implants, such as squamous cell carcinoma (Gallego et al, 2008) osteosarcoma (McGuff et al, 2008 and plasmacytoma of the mandible (Poggio, 2007). It is of note that TiO 2 was classified by the International Agency for Cancer Research, as possibly carcinogenic to humans (Group 2B) (Baan et al, 2006).…”

Section: Clinical Implications Of Corrosionmentioning

confidence: 99%

Systemic and Local Tissue Response to Titanium Corrosion

Olmedo¹,

Tasat²,

Duffó³

et al. 2012

Pitting Corrosion

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Section: Clinical Implications Of Corrosionmentioning

confidence: 99%

Systemic and Local Tissue Response to Titanium Corrosion

Olmedo¹,

Tasat²,

Duffó³

et al. 2012

Pitting Corrosion

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“…Features, such as ionic valence, particle concentration and size, and hypersensitivity, have been proposed to explain the potential association between malignant transformation and a metallic implant 15 . Regarding titanium specifically, there are reports of neoplasia, such as squamous cell carcinoma, 16 osteosarcoma, 17 and plasmacytoma of the mandible, 18 in association with dental implants. It is noteworthy that TiO 2 was classified by the International Agency for Cancer Research, an agency forming part of the World Health Organization of the United Nations, as possibly carcinogenic to humans (Group 2B) 19 …”

mentioning

confidence: 99%

Oral Mucosa Tissue Response to Titanium Cover Screws

Olmedo

Paparella

Spielberg³

et al. 2012

Journal of Periodontology

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“…In 2007, Dib et al (21) presented a case of a woman with metastasis around osseointegrated implants produced by a breast adenocarcinoma, which were diagnosed at the same time. In 2008, Gallego et al (22) presented a case of a patient without any risk factors, with a history of oral lichen planus, who subsequently presents a carcinoma in situ in another location. The patient is treated with a resection of the area and rehabilitated with implants; however, due to the recurrence of carcinoma, a mandibular resection next to the implants is performed.…”

Section: Discussionmentioning

confidence: 99%

Relationship between oral cancer and implants: clinical cases and systematic literature review

Jané-Salas¹,

López‐López²,

Roselló-Llabrés³

et al. 2012

Med Oral

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The use of implants for oral rehabilitation of edentulous spaces has recently been on the increase, which has also led to an increase in complications such as peri-implant inflammation or periimplantitis. Chronic inflammation is a risk factor for developing oral squamous cell carcinoma (OSCC). Objectives: To review the literature of cases that associate implant placement with the development of oral cancer. Study design: We present two clinical cases and a systematic review of literature published on the relationship between oral cancer and implants. Results: We found 13 articles published between the years 1996 and 2009, referencing 18 cases in which the osseointegrated implants are associated with oral squamous cell carcinoma. Of those, 6 articles were excluded because they did not meet the inclusion criteria. Of the 18 cases reported, only 7 cases did not present a previous history of oral cancer or cancer in other parts of the body. Conclusions: Based on the review of these cases, a clear cause-effect relationship cannot be established, although it can be deduced that there is a possibility that implant treatment may constitute an irritant and/or inflammatory cofactor which contributes to the formation and/or development of OSCC. Key words: Cancer, oral cancer, dental implants, oral squamous cell carcinoma, dental implants complications.

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Oral Squamous Cell Carcinoma Associated With Symphyseal Dental Implants

Cited by 49 publications

References 8 publications

Systemic and Local Tissue Response to Titanium Corrosion

Systemic and Local Tissue Response to Titanium Corrosion

Oral Mucosa Tissue Response to Titanium Cover Screws

Relationship between oral cancer and implants: clinical cases and systematic literature review

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