Oral submucous fibrosis: A clinico-histopathological study in Chennai

Kumar, Kiran; Saraswathi, TR; Ranganathan, K; Devi, Mutum Sangeeta; Joshua, Elizabeth

doi:10.4103/0970-9290.33785

Cited by 92 publications

(53 citation statements)

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“…Analysis of the demographic data of the sample revealed a male:female ratio of 2.7:1. A majority of studies published prior to 1990 reveal a female predominance, 6 while more recent studies indicate a male predilection, 14,15,19 similar to our data. However, the reason for this discrepancy observed in the sex distribution over the years is unknown and further research is needed.…”

Section: Discussionsupporting

confidence: 91%

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Relationship between thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis

Jayasooriya

Jayasinghe

Tilakaratne

2011

J of Invest & Clin Dent

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Section: Discussionsupporting

confidence: 91%

“…Nevertheless, most of the research on OSMF deals mainly with the isolated changes that occur in the connective tissue or the epithelium 11–15 . However, the outcome of the disease depends on the development of squamous cell carcinoma, which is influenced by fibrosis in the corium.…”

Section: Introductionmentioning

confidence: 99%

Relationship between thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis

Jayasooriya

Jayasinghe

Tilakaratne

2011

J of Invest & Clin Dent

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“…),[411] Stage-I were 12 cases (30%), Stage-II were 18 cases (45%) and Stage-III were ten cases (25%) [Table 1], and according to histopathological grading (Utsunomiya H and et al . ),[412] early stage were 12 cases (30%), intermediate stage were 18 cases (45%) and advanced stage were ten cases (25%) [Table 2].…”

Section: Resultsmentioning

confidence: 99%

“…These cases were staged clinically according to Kiran Kumar et al . [411] (Stage-I: Mouth opening >45 mm; Stage-II: Restricted mouth opening 20–44 mm; Stage-III: Mouth opening <20 mm), [Figure 1] and histopathologically were graded according to Utsunomiya H, Tilakratne WM, Oshira K et al . [Figure 2].…”

Section: Methodsmentioning

confidence: 99%

Estimation of hemoglobin, serum iron, total iron-binding capacity and serum ferritin levels in oral submucous fibrosis: A clinicopathological study

Thakur

Guttikonda

2017

J Oral Maxillofac Pathol

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Introduction:Oral submucous fibrosis (OSMF) is also considered as an Asian version of sideropenic dysphagia, wherein chronic iron deficiency leads to mucosal susceptibility to irritants, such as chillies and areca nut products. Hemoglobin (Hb) levels, in particular, serum iron levels, are considered as biochemical indicators for nutritional assessment. Serum iron content can thus be a predictor for the progression of the condition, and there appears to be an association between serum iron content and oral carcinogenesis. Therefore, biochemical assessment of oral precancerous conditions may help in early diagnosis and prognosis. Hence, the present study was aimed to evaluate Hb, serum iron, total iron-binding capacity (TIBC) and serum ferritin in OSMF patients.Materials and Methods:Forty cases of OSMF were staged clinically and graded histopathologically to assess the levels of Hb, serum iron, TIBC and serum ferritin and compared with normal subjects. The results were compared using t-test, ANOVA, and Tukeys multiple post hoc procedures.Results:It was observed that the levels of Hb, serum iron and serum ferritin levels gradually reduced in OSMF patients compared with controls and as the clinical stage and histological grade of OSMF progressed with a statistically significant P < 0.05. It was observed that the levels of TIBC gradually increased in OSMF patients compared with controls and as the clinical stage and histological grade of OSMF progressed with a statistically significant P < 0.05.Conclusion:The Hb, serum iron and serum ferritin levels in OSMF patients were reduced and TIBC increased as compared with controls and as the clinical stage and histological grade of OSMF advances indicating their role as a reliable biochemical indicator.

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“…Also, desensitizing agent along with regular clinical and radiographic follow-up could be helpful. 5,6 …”

Section: Introductionmentioning

confidence: 99%

Multiple talon cusps on maxillary central incisor: A case report

S¹,

Pr²,

Yadav³

et al. 2017

J Dent Res Dent Clin Dent Prospects

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Dental anomalies affecting the teeth are relatively common. Simultaneous occurrence of multiple dental abnormalities in a single tooth is uncommon and relatively rare. One such abnormality routinely encountered in dental clinics is the talon cusp. It is also referred to as dens evaginatus, characterized by the presence of an accessory cusp-like structure projecting from the cingulum of anterior teeth. It has an increased predilection for maxillary teeth and permanent dentition. Although numerous cases of talon cusp have been reported in the literature, occurrence of multiple talon cusps in maxillary central incisors has not been found in the literature. This case report highlights the presence of talon cusps in maxillary anterior teeth with multiple impacted supernumerary teeth.

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Oral submucous fibrosis: A clinico-histopathological study in Chennai

Cited by 92 publications

References 0 publications

Relationship between thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis

Relationship between thickness of fibrosis and epithelial dysplasia in oral submucous fibrosis

Estimation of hemoglobin, serum iron, total iron-binding capacity and serum ferritin levels in oral submucous fibrosis: A clinicopathological study

Multiple talon cusps on maxillary central incisor: A case report

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