2018
DOI: 10.1016/j.oraloncology.2018.06.014
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Oral tongue carcinoma among young patients: An analysis of risk factors and survival

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Cited by 59 publications
(68 citation statements)
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References 33 publications
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“…The influence of age and gender on the prognosis of OSCC patients has been investigated in some recent studies, but the results were generally controversial, which reflect variations in a large number of factors, such as the time span allowed for the collection of cases, samples size, prevalence of risk factors, time elapsed since diagnosis, access to healthcare services, geographic location, and global trends in OSCC. Some of the studies claimed that prognosis at a young age was similar (Blanchard et al, ; de Morais et al, ; Farquhar et al, ; Martinez et al, ), worse (Zhang et al, ), or better (Sommers et al, ) compared to that of older patients. We found that male gender was associated with a poorer prognosis, which was in accordance with previous studies (Ong, Murphy, Smith, Kanatas, & Mitchell, ; Santos et al, ).…”
Section: Discussionmentioning
confidence: 99%
“…The influence of age and gender on the prognosis of OSCC patients has been investigated in some recent studies, but the results were generally controversial, which reflect variations in a large number of factors, such as the time span allowed for the collection of cases, samples size, prevalence of risk factors, time elapsed since diagnosis, access to healthcare services, geographic location, and global trends in OSCC. Some of the studies claimed that prognosis at a young age was similar (Blanchard et al, ; de Morais et al, ; Farquhar et al, ; Martinez et al, ), worse (Zhang et al, ), or better (Sommers et al, ) compared to that of older patients. We found that male gender was associated with a poorer prognosis, which was in accordance with previous studies (Ong, Murphy, Smith, Kanatas, & Mitchell, ; Santos et al, ).…”
Section: Discussionmentioning
confidence: 99%
“…In addition, younger OSCC patients without major risk factors have a potential to have unknown biologic backgrounds. The prognosis of younger OSCC patient is a conflicting issue (Chang et al, 2013), but has been speculated as unfavorable compared to older patient in general (Farquhar et al, 2018;Son & Kapp, 1985;Zhang et al, 2017).…”
Section: Introductionmentioning
confidence: 99%
“…Although advanced diagnostic strategies and therapies, including surgery, chemotherapy and radiotherapy, are widely used, the possibility of complete recovery is remote (8,9). Therefore, a complete recognition of the molecular mechanisms involved in the multi-step processes of TSCC carcinogenesis and progression could provide more effective therapeutic targets for TSCC treatment (10,11).…”
Section: Introductionmentioning
confidence: 99%