Oral Transmucosal Fentanyl Citrate in the Management of Dyspnea Crises in Cancer Patients

Benítez-Rosario, Miguel Ángel; Martín, Antonio Salinas; Feria, Manuel

doi:10.1016/j.jpainsymman.2005.10.002

Cited by 40 publications

(21 citation statements)

References 5 publications

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“…20 The other OTFC study started with the same doses that the patient used for breakthrough pain. 17 Most of the studies did not provide sufficient information about the titration process, which was only described in seven studies. 17,20e22,24,28,29 For OTFC, titration was done by administering a second dose after 30 minutes, if the patient had not experienced breathlessness relief of 50%.…”

Section: Fentanyl Starting Dose Dose Titration Procedures and Effecmentioning

confidence: 99%

“…18,20,22,23,26,29 The Numerical Rating Scale was presumably used in one study, but this was not explicitly stated. 17 Six studies did not indicate any measurement tool. 19,21,24,25,27,28 Only one study measured the time to onset of breathlessness relief.…”

Section: Fentanyl Starting Dose Dose Titration Procedures and Effecmentioning

confidence: 99%

“…Only four studies contained information about patient satisfaction. 17,22,28,29 Adverse Effects Adverse effects of fentanyl were reported in five studies. 17e21 Somnolence and dizziness were the most common adverse effects (n ¼ 19).…”

Section: Fentanyl Starting Dose Dose Titration Procedures and Effecmentioning

confidence: 99%

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Fentanyl for the Relief of Refractory Breathlessness: A Systematic Review

Simon

Köskeroglu

Gaertner

et al. 2013

Journal of Pain and Symptom Management

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Section: Fentanyl Starting Dose Dose Titration Procedures and Effecmentioning

confidence: 99%

Section: Fentanyl Starting Dose Dose Titration Procedures and Effecmentioning

confidence: 99%

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Fentanyl for the Relief of Refractory Breathlessness: A Systematic Review

Simon

Köskeroglu

Gaertner

et al. 2013

Journal of Pain and Symptom Management

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“…Les études n'ont pas retenu d'efficacité pour la morphine en nébu-lisation. Il serait intéressant de savoir si le fentanyl, plus maniable chez l'insuffisant rénal, est efficace dans le traitement de la dyspnée terminale : un rapport de cas a été publié sur l'utilisation du fentanyl transmuqueux oral dans le traitement des accès de dyspnée aiguë, chez des patients cancéreux [9].…”

Section: Chez Un Patient Déjà Sous Traitement Morphiniqueunclassified

Comment soulager un patient dyspnéique en fin de vie ?

Voisin-Saltiel

2015

La Presse Médicale

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“…Likewise, case series of intranasal and transmucosal routes of fentanyl administration have shown benefit (35)(36)(37). Given that the genesis of breathlessness is multi-factorial, it is not surprising that benefit seen in uncontrolled studies may reduce or disappear when trials are blinded and randomised, for example, using "before and after" comparisons can exaggerate treatment effects by 61% compared with controlled studies(38).…”

Section: Effective Routes Of Administration (Oral Parenteral)mentioning

confidence: 99%

The Evidence Base for Oxygen for Chronic Refractory Breathlessness: Issues, Gaps, and a Future Work Plan

Johnson

Abernethy

Currow

2013

Journal of Pain and Symptom Management

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Please note that any alterations made during the publishing process may not appear in this version."NOTICE: this is the authors' version of a work that was accepted for publication in the Journal of Pain and Symptom Management. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Cities. Published Journal Articles (PJAs) Definition: A published journal article (PJA) is the definitive final record of published research that appears or will appear in the journal and embodies all value-adding publisher activities including copy-editing, formatting and (if relevant) pagination. Policy: Elsevier guarantees each PJA's authenticity, we work with others (e.g. national libraries) to preserve them for posterity and in perpetuity, and we invest to drive their usage. We strictly apply an absolute guideline regarding their location: every PJA will reside only on a completely controlled site because this is the only way that we as the publisher can guarantee each PJA's permanence, authenticity and that it is not altered. The continued viability of scholarly journals and their PJAs is also important to the research community. Publishers invest significant time, money and resources to create, maintain and develop both journals' reputations and the publishing process. The distribution of PJAs is therefore also subject to strict guidelines so that journals' ability to recoup the investments required to create them are not compromised. An author may use the PJA for personal use and internal institutional use (see above for definitions of these terms). In the interest of safeguarding the correct scientific record, however, Elsevier does not permit the posting of PJAs (Elsevier-provided PDF or HTML files) on any open websites. This is to ensure that the final published version of an article, which has been edited and peer-reviewed according to the publishing standards of an Elsevier journal, is always recognized as such only via the journal itself, whether in print or electronic format. PJAs may not be used for commercial use or for systematic distribution (see above for definitions of these terms). AbstractBreathlessness or "shortness of breath", medically termed dyspnoea, remains a devastating problem for many people and those who care for them. As a treatment intervention, administration of opioids to relieve breathlessness is an area where progress has been made with the development of an evidence base. As evidence in support of opioids has accumulated, so has our collective understanding about trial methodology, research collaboration and infrastructure that is crucial to generate reliable research results for palliative care clinical settings.Analysis of achievements to date and what it takes to accomplish these studies provides important insights into knowledge g...

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Oral Transmucosal Fentanyl Citrate in the Management of Dyspnea Crises in Cancer Patients

Cited by 40 publications

References 5 publications

Fentanyl for the Relief of Refractory Breathlessness: A Systematic Review

Fentanyl for the Relief of Refractory Breathlessness: A Systematic Review

Comment soulager un patient dyspnéique en fin de vie ?

The Evidence Base for Oxygen for Chronic Refractory Breathlessness: Issues, Gaps, and a Future Work Plan

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