Oral tuberculosis: a clinical evaluation of 42 cases

Abstract

OBJECTIVES: A retrospective review of a large series of oro‐facial cases of tuberculosis to analyse clinical, histo‐pathological, and radiological aspects, as well as those of chemotherapy. MATERIALS AND METHODS: A total of 42 cases of tuberculosis of the oro‐facial region were examined. Thirteen patients had a primary form and 29 a secondary form of the disease. Diagnosis was based on careful clinical examination, Mantoux reaction, histopathological examination, microbiological cultures and immunological investigation with the detection of antibodies against Mycobacteria in the patients' serum (ELISA). RESULTS: Cases examined consisted of 27 males and 15 females. The age range was 3 to 73 years (mean age 31 years). Clinical manifestations comprised oral ulcers in 69.1%, bone involvement in 21.4%, and salivary gland and/or lymph node involvement in 14.3%. A total of 79.4% patients with secondary disease had pulmonary lesions, 15 of whom showed clinical and radiological signs of activity; there was one case of bilateral renal lesions and two of skin lesions. CONCLUSIONS: Oro‐facial tuberculosis is often difficult to diagnose and it should be an important consideration in the differential diagnosis of lesions that appear in the oral cavity. The most important diagnostic tools remain a careful clinical evaluation, biopsy for histologic study, as well as acid‐fast stains, culture, and immunological assays, and skin testing.

Dental signs attributed to congenital syphilis and its treatments in the Hamann-Todd Skeletal Collection

“…Clinical cases of tuberculosis in children (Mignogna et al 2000;Ito et al 2005;Ebenezer et al 2006), have not shown any type of enamel hypoplasia nor the dental abnormalities resembling those described in the cases above. In skeletal cases of possible tuberculosis, dental abnormalities including linear enamel hypoplasia (Matos et al 2011;Bedić et al 2015), bands of decreased enamel thickness and carious lesions have been observed (Formicola et al 1987).…”

Ulcération linguale avec dysphagie à l’origine du diagnostic d’une tuberculose pulmonaire

“…Les lésions buccales de la tuberculose peuvent être primitives (20 % des cas) ou secondaires à une localisation pulmonaire (80 % des cas) [14]. Le mécanisme de la tuberculose primitive est incertain : le bacille serait directement inoculé dans la muqueuse buccale [15]. La tuberculose secondaire affecte plus fréquemment les personnes âgées.…”

Comparison of clinical aspects and Mantoux test in tuberculosis versus non-tuberculosis superficial lymphadenitis

“…T uberculosis (TB) of the superficial lymph nodes is the most common form of extra pulmonary tuberculosis in children, and it is the most common complication of a correlation between lymph node tuberculosis and the location, distribution and amount of the infected glands. [10][11][12] Enlargement of the lymph nodes outside the cervical area indicates a serious form of TB with systemic process. 7,13 Another opinion stated that multiple process is frequently found in the enlargement of superficial lymph nodes caused by MTB.…”