Oral Viral Infections

Clarkson, Earl; Mashkoor, Fatima; Abdulateef, Saif

doi:10.1016/j.cden.2016.12.005

Cited by 41 publications

(23 citation statements)

References 2 publications

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“… 23 In the oral mucosa, HSV lesions appear as ulcerative coalescent lesions after three to four weeks of chemotherapy or HSCT. 24 In this study, oral HSV infection was observed in 5% of the patients. From the four patients with HSV infection, only one had been submitted to HSCT, and this patient was hospitalized due to fever.…”

Section: Discussionmentioning

confidence: 53%

The frequency of oral conditions detected in hematology inpatients

Gomes

Silva

Noce

et al. 2018

Hematology, Transfusion and Cell Therapy

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BackgroundOral manifestations may be the first signs of hematologic diseases, and may occur due to the disease itself or to treatment.ObjectiveTo evaluate the frequency and types of oral conditions presented by patients on a hematology ward.MethodsData were collected by oral examinations during weekly visits to a hematology ward. Six trained dentists performed the oral assessment based on the principles of oral semiology. All patients who accepted to be examined were included in the study. Patients who were unavailable or unable to have oral examinations were excluded. Data were recorded on protocol forms and in the electronic records of the institution. A descriptive analysis was performed.ResultsSeventy-nine patients were included in the analysis; 50.6% were female and the mean age was 41.49 years. The most common reasons for hospitalization were chemotherapy and complications (81%), relapse (13.9%) and pre-transplant preparation (5%). The most frequent underlying diseases were multiple myeloma (17.7%), acute myeloid leukemia (15.4%) and acute lymphocytic leukemia (11.5%). Oral conditions were found in 36 (45.6%) patients, some of whom presented more than one condition. The most common oral conditions were dry lips (12.6%), mucositis (10.1%), petechiae (8.9%) and candidiasis (7.6%). Of the detected oral conditions, 56.9% were related to the underlying disease or chemotherapy and 20.2% were not related to the disease.ConclusionThis study shows the types and frequency of oral conditions observed in hematological inpatients. Awareness of these conditions is important for prevention and planning the care of patients with hematological diseases.

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Section: Discussionmentioning

confidence: 53%

The frequency of oral conditions detected in hematology inpatients

Gomes

Silva

Noce

et al. 2018

Hematology, Transfusion and Cell Therapy

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“…[77] To date, systemic administration of antiviral drugs is still the most common strategy for treating oral virus infections. [77] Very few local administration strategies are available in the literature and topical administration of antiviral agents, such as creams for labial herpes, is the only class of local drug delivery strategy available commercially. [1] The use of nanoparticles for the delivery of antiviral drugs is an exciting field of research.…”

Section: Antiviral Deliverymentioning

confidence: 99%

“…[ 76 ] Other human herpes infections include the HHV‐2 virus that causes genital herpes, the HHV‐3 virus that causes chickenpox and herpes zoster, the HHV‐4 (Epstein‐Barr) and HSV‐5 (cytomegalovirus) viruses that cause infectious mononucleosis, the HHV‐6 and HHV‐7 viruses that cause roseola (a viral disease causing high fever and a skin rash in small children), and the HHV‐8 virus that causes Kaposi's sarcoma in people with acquired immunity deficiency syndrome. [ 77 ] To date, systemic administration of antiviral drugs is still the most common strategy for treating oral virus infections. [ 77 ] Very few local administration strategies are available in the literature and topical administration of antiviral agents, such as creams for labial herpes, is the only class of local drug delivery strategy available commercially.…”

Section: Antiviral Deliverymentioning

confidence: 99%

Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management

et al. 2021

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The oral cavity and oropharynx are complex environments that are susceptible to physical, chemical, and microbiological insults. They are also common sites for pathological and cancerous changes. The effectiveness of conventional locally-administered medications against diseases affecting these oral milieus may be compromised by constant salivary flow. For systemically-administered medications, drug resistance and adverse side-effects are issues that need to be resolved. New strategies for drug delivery have been investigated over the last decade to overcome these obstacles. Synthesis of nanoparticle-containing agents that promote healing represents a quantum leap in ensuring safe, efficient drug delivery to the affected tissues. Micro/nanoencapsulants with unique structures and properties function as more favorable drug-release platforms than conventional treatment approaches. The present review provides an overview of newly-developed nanocarriers and discusses their potential applications and limitations in various fields of dentistry and oral medicine.

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“…Después del período agudo, la infección puede persistir hasta 18 meses en la faringe y reaparecer en forma intermitente. 16 En la fase inicial, las células Natural Killer, células supresoras y algunos linfocitos T citotóxicos inespecíficos llevan a cabo la respuesta inmune tras la infección. 5,16 Posteriormente, las células T CD8+ citotóxicas específicas frente a proteínas de membrana del VEB destruyen las células infectadas y originan la mayoría de los síntomas de la MI.…”

Section: Epidemiologíaunclassified

Virus de Epstein-Barr y su relación con la estomatología pediátrica. Una revisión narrativa

Rincón-Amador

Fragoso-Ríos

2021

CyRS

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Introducción. El Virus de Epstein-Barr (VEB) pertenece a la familia Herpesviridae y se clasifica como herpesvirus humano 4 (HVH-4). La prevalencia estimada a nivel mundial de infección por VEB rebasa el 95%. La mononucleosis infecciosa (MI), es una enfermedad sistémica producida en el 90% de ocasiones por el virus de VEB y que infecta al 95% de la población. Además, existe evidencia de que el VEB es un factor de riesgo para numerosas enfermedades inflamatorias orales como liquen plano oral (LPO), enfermedad periodontal y síndrome de Sjögren. La actualización del personal en este ámbito es fundamental para asegurar que las medidas se lleven a cabo correctamente. Objetivo. Presentar el estado del arte del conocimiento sobre el VEB y su relación con la estomatología pediátrica. Desarrollo. Se identificaron aquellos artículos que estudiaron las generalidades del VEB y de la MI en pacientes pediátricos a través de una revisión exhaustiva de la literatura. Se incluyeron artículos de investigación y revisión para la evaluación de esta relación. Conclusión. Debido a que la infección por VEB tiene una alta prevalencia, el estomatólogo general y pediatra deben tener conocimiento suficiente de los signos y síntomas de MI que se puedan presentar en la consulta debido a una infección sintomática por este virus, de esta manera podrá realizar un diagnóstico de la salud general del paciente y brindar una atención dental adecuada.

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Oral Viral Infections

Cited by 41 publications

References 2 publications

The frequency of oral conditions detected in hematology inpatients

The frequency of oral conditions detected in hematology inpatients

Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management

Virus de Epstein-Barr y su relación con la estomatología pediátrica. Una revisión narrativa

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