Oral viscous budesonide can be successfully delivered through a variety of vehicles to treat eosinophilic esophagitis in children

Lee, Ju Hee; Shuker, Michelle; Brown‐Whitehorn, Terri; Cianferoni, Antonella; Gober, Laura; Muir, Amanda B.; Verma, Ritu; Liacouras, Chris A.; Spergel, Jonathan M.

doi:10.1016/j.jaip.2016.02.005

Cited by 30 publications

(18 citation statements)

References 6 publications

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“…Budesonide can be administered by ingestion of the nebulized formulation, but most providers favor using a viscous slurry. In this case, the content of a budesonide respule is added to a thickening agent, such as sucralose, though other vehicles including honey, agave nectar, Neocate Nutra, and applesauce are also frequently used 80,81 . Typically 1 mg of budesonide will be mixed with 0.5–1 teaspoons of sweetener 81 .…”

Section: Treatmentmentioning

confidence: 99%

Diagnosis and Management of Eosinophilic Esophagitis

Wilson

McGowan

2018

Immunology and Allergy Clinics of North America

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Section: Treatmentmentioning

confidence: 99%

Diagnosis and Management of Eosinophilic Esophagitis

Wilson

McGowan

2018

Immunology and Allergy Clinics of North America

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“…Budesonide is administered orally after the contents of a vial used for nebulization are mixed with a thickening agent to increase the viscosity of the solution which, theoretically, slows its transit over the esophageal lining [ 23 ]. A variety of sweeteners/vehicles can be chosen for increasing viscosity, including sucralose, applesauce, and honey [ 52 ].…”

Section: Treatmentmentioning

confidence: 99%

Eosinophilic esophagitis

Carr

Chan

Watson

2018

Allergy Asthma Clin Immunol

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Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies. Patients with EoE should be referred to an allergist for optimal management, which may include dietary modifications and pharmacologic agents such as corticosteroids, and for the diagnosis and management of comorbid atopic conditions. Mechanical dilation of the esophagus may also be necessary. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.

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“…Budesonide is administered orally after the contents of a vial used for nebulization are mixed with a thickening agent to increase the viscosity of the solution which, theoretically, slows its transit over the esophageal lining [24]. A variety of sweeteners/vehicles can be chosen for increasing viscosity, including sucralose, applesauce, and honey [60].…”

Section: Treatmentmentioning

confidence: 99%

Correction to: Eosinophilic esophagitis

Carr

Chan

Watson

2019

Allergy Asthma Clin Immunol

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Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies. Patients with EoE should be referred to an allergist for optimal management, which may include dietary modifications and pharmacologic agents such as proton pump inhibitors (PPI) and corticosteroids, and for the diagnosis and management of comorbid atopic conditions. Mechanical dilation of the esophagus may also be necessary. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.

show abstract

Oral viscous budesonide can be successfully delivered through a variety of vehicles to treat eosinophilic esophagitis in children

Cited by 30 publications

References 6 publications

Diagnosis and Management of Eosinophilic Esophagitis

Diagnosis and Management of Eosinophilic Esophagitis

Eosinophilic esophagitis

Correction to: Eosinophilic esophagitis

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