Oral vs Intratympanic Corticosteroid Therapy for Idiopathic Sudden Sensorineural Hearing Loss

Abstract

clinicaltrials.gov Identifier: NCT00097448.

Effects and Prognostic Factors of Acupuncture Treatment for Idiopathic Sudden Sensorineural Hearing Loss

“…If the 10 patients within 2 weeks from the onset were excluded to eliminate the effect from nature spontaneous recovery, 43.5% patients (27/62) showed clear or partial improvement. These results were similar to or higher than average recovery rate of other studies especially considering the time interval from onset of ISSHL to start treatment ( Xenellis J et al, 2006;Haynes DS et al, 2007;Raymundo IT et al, 2010;Wu HP et al, 2011;Rauch SD et al, 2011;Park MK et al, 2011).…”

“…We decided the criterion valuation basis for effectiveness at least 10 dB decrease in PTA of contiguous 4 frequencies (250, 500, 1000, 2000 Hz) because most of patients visited our clinic after they failed to conventional therapies, so we considered that 10 dB was reasonable comparing other studies (Xenellis J et al, 2006;Rauch SD et al, 2011;Wu HP et al, 2011) After completing the AT, 50% patients (36/72) showed clear or partial improvement. If the 10 patients within 2 weeks from the onset were excluded to eliminate the effect from nature spontaneous recovery, 43.5% patients (27/62) showed clear or partial improvement.…”

Comparison of Long-Term Outcome of Intratympanic Dexamethasone Therapy between Acute Noise-Induced Tinnitus and Acute Idiopathic Tinnitus

“…A randomized, large-scale, multicenter study demonstrated that intratympanic corticosteroids have the same efficacy as oral steroids for the treatment of sudden SNHL [29] . Although many studies have not shown a positive effect of intratympanic steroid on tinnitus, we demonstrated the therapeutic effects of ITD limited to the acute tinnitus cases in a recent double-blind, randomized, and controlled trial [18] .…”

Diagnostic Accuracy of Screening MR Imaging Using Unenhanced Axial CISS and Coronal T2WI for Detection of Small Internal Auditory Canal Lesions

“…For patients who present with symptoms of acute vertigo with or without sudden sensorineural hearing loss, the optimal treatment will be a short course of high-dose steroids, regardless of the imaging findings. 20,21 In the setting of suspected sarcoidosis or primary malignancy, a contrast-enhanced examination is warranted rather than a screening examination. Furthermore, sarcoidosis or leptomeningeal metastases rarely present as isolated sensorineural hearing loss.…”