Orally transmitted acute Chagas disease in domestic travelers in Colombia

Prevalence of Trypanosoma cruzi infection in active military population of The Colombian National Army gathered in five departments

“…cruzi infections in different age groups, suggest that the greatest trouble is related to adults where about 3% (95% CI, 1.0–5.0) is infected with the parasite [15, 16]. This position suggests the need to include an adult serological screening that allows both the identification of asymptomatic patients who acquired the infection before consolidation of the National Transmission Interruption Program, as well as, cases that can be acquired during operational activities in areas with presence of vectors [10, 20, 25]. The identification of these cases could provide to the prevention of cardiac failures belong to the chronic phase, throughout chemotherapeutic management.…”

Chagas Cardiomyopathy: From Romaña Sign to Heart Failure and Sudden Cardiac Death

“…The transmission has importance over the others regarding public health because of feasibility in almost any region in the Amazon, Caribbean, and Andean regions and its relationship with a higher inoculum and more severe manifestations. The severe acute CD secondary to oral outbreaks is associated with higher rates of acute myocarditis, meningoencephalitis, and fatality cases, probably due to the sustained production of inducible pro-inflammatory cytokines, subsequently continued inflammation, and higher parasitization of cardiac muscle and the brain [ 19 ]. The largest oral outbreaks in Venezuela in different schools, with approximately 100 people affected, are mostly in children [ 20 , 21 ].…”

The Constant Threat of Zoonotic and Vector-Borne Emerging Tropical Diseases: Living on the Edge

“…The impact of these diseases and the establishment of local transmission in traditionally non-endemic areas, due to migration and travel, have been revealed over the last years. Diseases such as Chikungunya (11-16), Zika (17-24), Yellow Fever (25-28), Dengue (29)(30)(31)(32)(33), Oropouche, Madre de Dios virus, Iquitos virus (34,35), Mayaro Fever (36,37), Ebola (38)(39)(40)(41)(42), Nipah virus, arenaviruses such as Lassa (43), Machupo (44,45), Chapare (45,46), Junin (47), zoonotic Malaria (48), Severe Fever with Thrombocytopenia Syndrome (49), Plague (50), Crimean-Congo Hemorrhagic Fever, Acute Orally Transmitted Chagas Disease (51)(52)(53)(54), Visceral and Diffuse Cutaneous Leishmaniasis (55,56), Toxoplasmosis (57)(58)(59), Tick-Borne Diseases (60,61), Rift Valley Fever, Tuberculosis (62), Leprosy (63)(64)(65)(66)(67), Avian Influenza (68)(69)(70), Orthohantavirus (71)(72)…”

“…The impact of these diseases and the establishment of local transmission in traditionally non-endemic areas, due to migration and travel, have been revealed over the last years. Diseases such as Chikungunya ( 11 – 16 ), Zika ( 17 – 24 ), Yellow Fever ( 25 – 28 ), Dengue ( 29 – 33 ), Oropouche, Madre de Dios virus, Iquitos virus ( 34 , 35 ), Mayaro Fever ( 36 , 37 ), Ebola ( 38 – 42 ), Nipah virus, arenaviruses such as Lassa ( 43 ), Machupo ( 44 , 45 ), Chapare ( 45 , 46 ), Junin ( 47 ), zoonotic Malaria ( 48 ), Severe Fever with Thrombocytopenia Syndrome ( 49 ), Plague ( 50 ), Crimean-Congo Hemorrhagic Fever, Acute Orally Transmitted Chagas Disease ( 51 – 54 ), Visceral and Diffuse Cutaneous Leishmaniasis ( 55 , 56 ), Toxoplasmosis ( 57 – 59 ), Tick-Borne Diseases ( 60 , 61 ), Rift Valley Fever, Tuberculosis ( 62 ), Leprosy ( 63 – 67 ), Avian Influenza ( 68 – 70 ), Orthohantavirus ( 71 – 75 ), and Toxocariasis ( 76 , 77 ) have posed a significant impact to human health. Furthermore, zoonotic epidemics and pandemic coronaviruses, such as the Severe Acute Respiratory Syndrome (SARS), the Middle East Respiratory Syndrome (MERS) ( 78 – 82 ), and the ongoing SARS-CoV-2/COVID-19 ( 83 , 84 ) pandemic, have caused a profound economical and social disruption threatening to overwhelm public health systems globally ( 85 ) ( Table 1 ).…”