Orbital Complication of Allergic Fungal Rhino-sinusitis

Alzarei, Ali; Assiri, Kholood S.

doi:10.15344/2455-2356/2016/111

Cited by 5 publications

(4 citation statements)

References 15 publications

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“…In a study by Ali. H et al 9 the incidence of ocular manifestations in AFPS was 27 out of 60(0.45%) which was almost similar to that of our study. Male to female ratio is 1.25:1.…”

Section: Discussionsupporting

confidence: 92%

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Ocular manifestations and treatment outcome of allergic fungal pan sinusitis

Sharanabasamma¹,

Vaibhav

2022

IJOOO

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To know the incidence and treatment outcome of various ocular manifestations of allergic fungal pan sinusitis. A prospective study was conducted in a medical college hospital in south India for a period of 2 years which included all the cases of allergic fungal pansinusitis presented to the hospital. The cases were diagnosed by Bent-Kuhn criteria. The cases with ophthalmologic involvement were included in the study. CT scan of PNS, brain, orbit were done and the disease extent was noted. Cases with eye involvement were planned for surgical debridement after an initial prednisolone oral 1mg/kg over 2 weeks. Surgical debridement was done endoscopically by a team of ENT surgeon, oculoplastic surgeon and neurosurgeon. Histopathologic examination was done. Post-surgery the steroids were tapered over 2 weeks. Post operative follow up was done every day for first week followed by weekly once till a month and every 6 monthly once for a year in the form of clinical examination, CT scan was repeated after a week during post op period. In cases with suspected recurrence CT PNS was performed. Their outcomes were analyzed. 6 cases (33%) had ocular involvement. Proptosis was the most common (28%) finding followed by epiphora (22.2%), ophthalmoparesis (22.2%), diplopia (22.2%), ophthalmoplegia (11.%), complete loss of vision (5%). Surgical intervention led to early recovery in proptosis followed by others except with PL -ve case. Early treatment in AFPS prevents vision loss and has better outcomes.

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“…In a study by Ali. H et al 9 the incidence of ocular manifestations in AFPS was 27 out of 60(0.45%) which was almost similar to that of our study. Male to female ratio is 1.25:1.…”

Section: Discussionsupporting

confidence: 92%

“…Post-operative recovery was seen for proptosis initially in our study similar to that of study by Ali. H. et al 9 There was no recovery of vision in the case with optic nerve compression which remained PL-ve in spite of surgical debridement.…”

Section: Discussionmentioning

confidence: 90%

Ocular manifestations and treatment outcome of allergic fungal pan sinusitis

Sharanabasamma¹,

Vaibhav

2022

IJOOO

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“…In our study, 52% of our cases were presented with proptosis, and visual loss was recorded in only 2% of studded cases. According to Alzarei and Assiri (14) orbital complications were encountered: (26.7%) eye proptosis, (11.7%) diplopia and (6.7%) unilateral complete blindness. Proptosis of the eye responded well to surgical and postoperative treatment, but diplopia improved more slowly following surgical and medicinal treatment.…”

Section: Discussionmentioning

confidence: 99%

Relation between Complicated Allergic Fungal Rhinosinusitis and the Mycological Profile of the Isolated Fungal Species

Ahmed¹,

Mohamed²,

Mohamed³

et al. 2021

The Egyptian Journal of Hospital Medicine

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Background: Allergic fungal sinusitis is a non-invasive pansinusitis that occurs in young immunocompetent individuals, with a strong history of atopy and elevated levels of total immunoglobulin E and peripheral eosinophilia. Objective: The main target of the study was to know the relation between complicated allergic fungal sinusitis and the mycologic profile of the causative fungal species, as regards the genus and species of the isolated fungus, its antifungal susceptibility and its ability to produce destructive extracellular metabolic products and toxic agents. Patients and Methods: Our cross sectional research included 50 individuals diagnosed with complicated allergic fungal rhinosinusitis who attended to the ENT outpatient clinic. All the studied patients were evaluated by full history, complete ENT examination, radiological evaluation, laboratory investigations and endoscopic sinus surgery. Results: Aspergillus spp., particularly Aspergillus fumigatus and Aspergillus flavus, are the most often identified agents in allergic fungal rhinosinusitis. A multifaceted strategy to treat allergic fungal rhinosinusitis is necessary; surgery is the primary treatment for allergic fungal sinusitis. Corticosteroid treatment in its entirety is presently the gold standard of medical management, whereas alternative pharmacological treatments such as antifungals, antimicrobials, leukotriene modulators, and immunotherapy are reserved for those who are insufficiently responsive.. Conclusions: The most frequent kind of fungal rhinosinusitis is allergic fungal rhinosinusitis. It is found in immunecompetent youth who have a history of allergic rhinitis and/or asthma. Allergic fungal rhinosinusitis has a relatively slow and indolent clinical course, but results in the growth of bone walls, resulting in their thinning or weakening and final erosion.

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“…In another study by Al Dousary [ 33 ], he reported 16% of ophthalmic manifestations in patients with AFRS, with proptosis as the predominant presentation. Proptosis was found to be the most common presentation in two separate studies [ 34 , 35 ]. Al-Radadi and Alnoury [ 36 ] have reported a case that presented with a visual field defect without changes in visual acuity.…”

Section: Reviewmentioning

confidence: 99%

Allergic Fungal Rhinosinusitis in Saudi Arabia: A Review of Recent Literature

Alahmari¹

2021

Cureus

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Allergic fungal rhinosinusitis (AFRS) has been considered an enigma since it was first described four decades ago. Previous research has found that AFRS has multiple definitions and a poorly understood pathogenesis because it overlaps with other conditions and necessitates meticulous work and multiple diagnostic modalities to confirm the diagnosis. However, despite the expansion of medical and surgical treatments, recurrence still occurs. In this review, the recent literature on AFRS cases in Saudi Arabia with relevance to its epidemiology, diagnosis, and management was studied and compared with international data. PubMed, Google Scholar, and Cochrane Library were searched for original research and review articles with local data. There is an evident paucity and contradiction between local studies regarding the epidemiology, diagnostic methods, and management of AFRS. Hence, well-defined randomized controlled trials (RCTs) are needed for the treatment of this chronic recurrent disease.

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Orbital Complication of Allergic Fungal Rhino-sinusitis

Cited by 5 publications

References 15 publications

Ocular manifestations and treatment outcome of allergic fungal pan sinusitis

Ocular manifestations and treatment outcome of allergic fungal pan sinusitis

Relation between Complicated Allergic Fungal Rhinosinusitis and the Mycological Profile of the Isolated Fungal Species

Allergic Fungal Rhinosinusitis in Saudi Arabia: A Review of Recent Literature

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