Orbital Complications of Fibrous Dysplasia

Cranioorbital fibrous dysplasia: with emphasis on visual impairment and current surgical management

“…41 Other explanations include exophthalmos-induced optic nerve traction, sinus mucocele formation, with increased intraorbital pressure, spontaneous hemorrhage, bone cyst formation, or rare vascular events. 4,7,9,10,14,22,28,30,35,39,40 More recently, our group and others have questioned whether the most common cause of visual loss in fibrous dysplasia is indeed bone overgrowth-induced optic canal stenosis. This traditionally held belief may not be supported after careful scrutiny and critical analysis, particularly of cases in which quality CT or MR imaging studies and careful neuroophthalmological data are available.…”

Fi̇bröz Di̇splazi̇: Bi̇r Olgu Sunumu

“…2,3,[7][8][9] Bununla birlikte maksilla ve mandibula baş-boyun bölgesinde en sık tutulan alanlardır. 1 Ayrıca kraniofasial bölge tutulumu monostotik FD'li hastalarda poliostotik FD'li hastalara (%40-60) göre daha az görülmesine rağmen (%10-25) kraniofasial FD'li hastaların çoğu monostotiktir.…”

Surgery versus Watchful Waiting in Patients with Craniofacial Fibrous Dysplasia: A Meta-Analysis

“…Similarly, Chen et al reported that one-third of CFD patients will have visual deficits, and two-thirds will report some degree of visual disturbance if optic canal involvement is demonstrated by imaging [8]. Due to the potential risk of rapidly progressing visual deterioration and irreversible optic nerve atrophy, many studies suggest prophylactic decompression of the nerve in asymptomatic CFD patients with radiologic evidence of optic nerve compression [8,37,38]. Contrary to these studies, Lee et al reported in her sentinel study that the vast majority of asymptomatic patients with CFD will demonstrate normal vision despite radiological evidence of optic nerve compression, but this cohort did not include a group managed with optic nerve decompression [6].…”