Orbital compression syndrome in a Ugandan child with sickle cell disease: A case report

Abstract

Orbital compression syndrome is a rare acute complication of sickle cell disease that may impair vision. Assessment by a multidisciplinary team incorporates detailed history and physical examination, fundoscopy, and appropriate imaging to exclude infections or neoplasms. Supportive treatment is adequate unless there is evidence of life‐threatening space‐occupying lesion warranting surgery.

Massive spontaneous subdural hemorrhage mimicking dural venous thrombosis in a sickle cell adolescent, a rare case report

“…It results from a mutant beta globulin gene in which valine is substituted for glutamic acid at position 6 of the beta globulin chain of red blood cells causing the formation of sickled shape hemoglobin [ 1 ], which affects its oxygen carrying capacity and making it prone to destruction by the body causing anemia [ 2 ]. In Africa, about 300,000 children are born with sickle cell annually [ 3 ]. Tanzania alone accounts for 11,000 sickle cell disease births annually [ 4 ] making it one of the commonest hemoglobinopathy in this country.…”