Orbital Tumors

Peiffer, Robert L.; Simons, Kenneth B.

doi:10.1002/9780470376904.ch1

Cited by 6 publications

(12 citation statements)

References 24 publications

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“…Orbital tumors have been reported to arise from any tissue within the orbital cavity 1,2 . They may be primary, 3 metastatic, 4 or arise from local extension of tumors in the oral 5 or nasal cavity, 6 paranasal sinus, 7 or cranium 8 . In general, they are expansive and progressive, resulting in unilateral exophthalmos with variable globe deviation (i.e., strabismus).…”

Section: Introductionmentioning

confidence: 99%

Surgical management of orbital nodular granulomatous episcleritis in a dog

Barnes

Pearce

Berent

et al. 2010

Veterinary Ophthalmology

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A 27 kg, 6-year-old, male castrated German shorthaired pointer presented to the University of Missouri, Veterinary Teaching Hospital with the complaint of progressive exophthalmia of 2 years duration optical density (OD). Lack of retropulsion OD was noted on physical examination. Anterior segment examination OU and fundic examination OS did not reveal any abnormalities. Examination of the fundus OD revealed focal scleral indentation of the inferior nasal globe. The indentation changed location with globe movement OD. MRI and CT scan revealed a well-circumscribed, approximately 2 cm in diameter mass located caudal and ventral to the affected globe that appeared to communicate with the nictitating membrane with absence of any bony involvement. A modified lateral orbitotomy was recommended and performed to remove the orbital mass and nictitating membrane en-bloc. Histopathology and immunohistochemistry of the mass confirmed a diagnosis of nodular granulomatous episcleritis (NGE). Postoperatively, the dog developed absolute keratoconjunctivitis sicca (KCS). Examples of primary episcleral inflammation in the dog include diffuse episcleritis, NGE, nodular fasciitis, fibrous histiocytoma, proliferative conjunctivitis/keratoconjunctivitis, pseudotumor, and Collie granuloma. The etiology of these episcleral inflammations is presumed to be immune mediated. To our knowledge, this is the first report of NGE affecting the orbital region of a dog. Development of absolute KCS resulting from excision of the nictitating membrane is also supported by this case.

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Section: Introductionmentioning

confidence: 99%

Surgical management of orbital nodular granulomatous episcleritis in a dog

Barnes

Pearce

Berent

et al. 2010

Veterinary Ophthalmology

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“…Such disorders occur infrequently in animals and include immune‐mediated conditions and idiopathic orbital inflammation (IOI; otherwise known as orbital pseudotumor) 1, 2, 8. We consider that the term “pseudotumor” is less than ideal for these orbital inflammatory growths – we have thus adopted the most recent nomenclature from the human literature to promote cohesive cross‐translational understanding of the pathology while awaiting a more refined classification in companion species.…”

Section: Discussionmentioning

confidence: 99%

“…We consider that the term “pseudotumor” is less than ideal for these orbital inflammatory growths – we have thus adopted the most recent nomenclature from the human literature to promote cohesive cross‐translational understanding of the pathology while awaiting a more refined classification in companion species. Most orbital tumors are considered to be malignant with a poor to guarded prognosis 9, 10; by contrast, IOI is defined as benign, orbital inflammation without evidence of a specific local or systemic etiology 8, 11, 12, 13, 14. A common disorder in humans, IOI occurs most often between the third and fifth decades of life 8, 11, 13, 15.…”

Section: Discussionmentioning

confidence: 99%

“…Most orbital tumors are considered to be malignant with a poor to guarded prognosis 9, 10; by contrast, IOI is defined as benign, orbital inflammation without evidence of a specific local or systemic etiology 8, 11, 12, 13, 14. A common disorder in humans, IOI occurs most often between the third and fifth decades of life 8, 11, 13, 15. These lesions may be bilateral or alternating (ipsilateral remission followed by contralateral emergence) but typically present unilaterally, thus mimicking neoplasms 8, 15, 16, 17.…”

Section: Discussionmentioning

confidence: 99%

“…A common disorder in humans, IOI occurs most often between the third and fifth decades of life 8, 11, 13, 15. These lesions may be bilateral or alternating (ipsilateral remission followed by contralateral emergence) but typically present unilaterally, thus mimicking neoplasms 8, 15, 16, 17. Although nonmetastatic, IOI is locally aggressive, often leading to severe visual and oculomotor dysfunction, requiring surgical intervention 12, 13.…”

Section: Discussionmentioning

confidence: 99%

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Idiopathic sclerosing orbital inflammation mimicking a malignant spindle cell tumor in a dog

Rzechorzek

Smith

Schwarz

et al. 2016

Clinical Case Reports

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Key Clinical MessageA dog presented with a retrobulbar mass, diagnosed histopathologically as malignant spindle cell neoplasia. Emergence of analogous findings in the contralateral orbit prompted extended immunohistochemistry of the original mass and reassignment to idiopathic sclerosing orbital inflammation. Early incisional biopsy with extended immunohistochemical analysis should be considered for canine orbital tumors.

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Management of Orbital Diseases

Betbeze

2015

Topics in Companion Animal Medicine

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Orbital Tumors

Cited by 6 publications

References 24 publications

Surgical management of orbital nodular granulomatous episcleritis in a dog

Surgical management of orbital nodular granulomatous episcleritis in a dog

Idiopathic sclerosing orbital inflammation mimicking a malignant spindle cell tumor in a dog

Management of Orbital Diseases

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