As a valuable mineral resource, uranium is extensively utilized in nuclear power generation, radiation therapy, isotope labeling, and tracing. In order to achieve energy structure diversification, reduce dependence on traditional fossil fuels, and promote the sustainable development of energy production and consumption, research on the metallogenic mechanisms and related development technologies of uranium resources has been one of the focuses of China’s energy development. Sandstone-type uranium deposits make up approximately 43% of all deposits in China, making them the most prevalent form of uranium deposit there. Sandstone-type uranium deposits and hydrocarbon resources frequently coexist in the same basin in China. Therefore, this study summarizes the spatial and chronological distribution, as well as the geological characteristics, of typical sandstone-type uranium deposits in China’s hydrocarbon-bearing basins. From the perspectives of fluid action, geological structure, and sedimentary environment, the metallogenic mechanisms of sandstone-type uranium deposits in hydrocarbon-bearing basins are explored. According to the research, the rapid reduction effect of oil and gas in the same basin is a major factor in the generation of relatively large uranium deposits. Additionally, ions such as CO32− and HCO3− in hydrothermal fluids of hydrocarbon-bearing basins, which typically originate from dispersed oil and gas, are more conducive to uranium enrichment and sedimentation. This study provides guidance for efficient sandstone-type uranium deposit exploration and production in hydrocarbon-bearing basins and helps to achieve significant improvements in uranium resource exploitation efficiency.