Organ donation following brain stem death after ventricular assist device implantation

Mohite, Prashant N.; Popov, Aron Frederik; Zych, Bartłomiej; Dhar, Dhruva; Capoccia, Massimo; Simon, Andrè

doi:10.1177/0218492312470671

Cited by 5 publications

(2 citation statements)

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“…Neurologic events during LVAD support are associated with significant morbidity and mortality rates and can cause brainstem death. A patient with diagnosed brain death who is supported by a VAD and has preserved end-organ function can and should be considered for donating organs [ 79 ], including the liver, kidneys, and lungs. In some cases, organ donation has also occurred after cardiac death.…”

Section: Symptom Approachmentioning

confidence: 99%

Mechanical circulatory assist devices: a primer for critical care and emergency physicians

et al. 2016

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Mechanical circulatory assist devices are now commonly used in the treatment of severe heart failure as bridges to cardiac transplant, as destination therapy for patients who are not transplant candidates, and as bridges to recovery and "decision-making". These devices, which can be used to support the left or right ventricles or both, restore circulation to the tissues, thereby improving organ function. Left ventricular assist devices (LVADs) are the most common support devices. To care for patients with these devices, health care providers in emergency departments (EDs) and intensive care units (ICUs) need to understand the physiology of the devices, the vocabulary of mechanical support, the types of complications patients may have, diagnostic techniques, and decision-making regarding treatment. Patients with LVADs who come to the ED or are admitted to the ICU usually have nonspecific clinical symptoms, most commonly shortness of breath, hypotension, anemia, chest pain, syncope, hemoptysis, gastrointestinal bleeding, jaundice, fever, oliguria and hematuria, altered mental status, headache, seizure, and back pain. Other patients are seen for cardiac arrest, psychiatric issues, sequelae of noncardiac surgery, and trauma. Although most patients have LVADs, some may have biventricular support devices or total artificial hearts. Involving a team of cardiac surgeons, perfusion experts, and heart-failure physicians, as well as ED and ICU physicians and nurses, is critical for managing treatment for these patients and for successful outcomes. This review is designed for critical care providers who may be the first to see these patients in the ED or ICU.

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Section: Symptom Approachmentioning

confidence: 99%

Mechanical circulatory assist devices: a primer for critical care and emergency physicians

et al. 2016

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“…However, intracranial hemorrhages may also occur, and some patients become brain dead due to hematoma expansion. Although there is no pulsatile flow or systolic blood pressure level to follow to conduct the BD exam in these patients, there have been reports of patients declared BD, 38,39 but details of the BD exam were not published.…”

Section: Vagueness In Bd Prerequisites and The Objectivity Of Ancillamentioning

confidence: 99%

Modern Approach to Brain Death

Varelas

Lewis

2016

Semin Neurol

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People die either when their heart and respiration stop or when their brain irreversibly stops functioning. This latter mode of death by neurologic criteria (also called ) emerged after the development of ventilators and intensive care units in the late 1950s and 1960s. Brain death is universally accepted as a modern entity, but the complex process for declaring a patient brain dead is not uniformly followed across country and state lines or even hospital policies, creating unacceptable variability and risks for falsely pronouncing a patient dead. If, however, the declaring physician has expertise and diligently follows the steps that have been published in guidelines, this risk is mitigated. In this article, the authors describe the steps for brain death declaration, discuss how to avoid pitfalls, and examine the modern controversies regarding this medical reality.

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Neurologic Complications: Pathophysiology, Incidence, Types, Prevention, and Management

Colombo,

Ibeh,

Melmed

et al. 2023

Textbook of Transplantation and Mechanical Support for End‐Stage Heart and Lung Disease

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Organ donation following brain stem death after ventricular assist device implantation

Cited by 5 publications

References 5 publications

Mechanical circulatory assist devices: a primer for critical care and emergency physicians

Mechanical circulatory assist devices: a primer for critical care and emergency physicians

Modern Approach to Brain Death

Neurologic Complications: Pathophysiology, Incidence, Types, Prevention, and Management

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