“…Only 58 % of patients in group 4 had leukocytosis, and of those with leukocytosis, the value was high. Some patients had normal values, and that response was expected because the inflammatory response in this series reached its peak after 73 h and because the instauration of sepsis would eventually lead to a decreased WBC count or even leukopenia [2,4,5,11,12,[22][23][24][25][26]. In studies using various diagnostic intervals, the incidence of leukocytosis varied from 78 to 88 % [2,3]; however, in one study using three different diagnostic intervals, the presence of leukocytosis increased along a prolonged time of symptom evolution [12].…”