Organic Bipolar Disorder: An Unusual Neuropsychiatric Sequelae following Right Frontotemporal Injury

Ummar, Syed; Kumar, Naveen; Ramanathan, Shree Aarthi

doi:10.4103/0253-7176.183081

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…Another interesting case was reported by Agnihotri et al ,[ 39 ] depicting a 19-year-old male presenting with manic symptoms following administration of electroconvulsive therapy for schizophrenia. Finally, a case report by Ummar et al ,[ 40 ] presented a 49-year male with right frontotemporal contusion, who developed manic symptoms within 10 days of sustaining the injuries.…”

Section: Resultsmentioning

confidence: 99%

Research on clinical aspects of bipolar disorder: A review of Indian studies

Narula,

Pal,

Reddy

et al. 2024

Indian Journal of Psychiatry

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Background: Bipolar disorder is one of the severe mental disorders that are associated with significant morbidity of the patients. Despite advancements in our understanding about the disorder, it remains a challenging proposition to treat bipolar disorder, largely since the prophylactic treatment of the disorder requires assessment of complex clinical algorithms. The revisions of the classificatory systems have also changed the conceptualization of the disorder. In this background, we conducted a review of the Indian studies conducted on the clinical aspects of bipolar disorder. Methods: A narrative review was conducted with focus on the literature published from India. The databases searched included PubMed, Scopus, and Google Scholar, and articles published over the last 15 years by Indian authors were included for this review. Results: In our review, we could access a substantial volume of research published from India. We could identify studies that catered to most of the relevant themes in bipolar disorder including epidemiology, etiology, comorbidities, stigma, disability, clinical course, cognitive profile, pathways to care, and recovery. Conclusion: The research trajectory was in line with the research conducted elsewhere in the world. However, certain dissimilarities in terms of focus could also be observed. The possible reason behind this deviation could be the difference in clinical need and unique challenges faced in the management and rehabilitation of patients in bipolar disorder in Indian scenario.

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Section: Resultsmentioning

confidence: 99%

Research on clinical aspects of bipolar disorder: A review of Indian studies

Narula,

Pal,

Reddy

et al. 2024

Indian Journal of Psychiatry

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Neuropsychiatry and Traumatic Brain Injury

Scicutella

2019

Acquired Brain Injury

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Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review

King,

Elliott,

Pitman

2024

Discov Ment Health

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Steroid-induced neuropsychiatric sequelae are common, and pose significant risks to people usually receiving glucocorticoids in the context of physical illness. Steroid-induced mania and hypomania are the most common of the acute complications, yet despite great progress in understandings in neurophysiology there are no recent studies which review the factors which might predict who will experience this severe complication, nor are there consensus guidelines on management. We report the unusual case of a woman in her 50s admitted to a psychiatric unit with steroid-induced mania despite compliance with two mood stabilisers, several days after the administration of a Dexamethasone and Docetaxel chemotherapy regime adjunctive to lumpectomy for breast cancer. She had previously been diagnosed with an organic affective disorder (with classical bipolar 1 pattern) following severe ventriculitis related to ventricular drain insertion for obstructive hydrocephalus secondary to a colloid cyst. She had no psychiatric illness before this brain injury, but has a maternal history of idiopathic bipolar 1 affective disorder. Her episode of steroid-induced mania resolved following use of sedative medications, continuation of her existing mood stabilisers, and reductions of the steroid dosing in collaboration with her oncology team, which also protected her from further manic relapses during continued chemotherapy. Established mental illness, a family history, and acquired brain injury may reflect risk factors for steroid-induced mania through currently unclear pathways. Future epidemiological studies could better confirm these observations, and basic neuroscience may look to further explore the role of extrinsic glucocorticoids in the pathophysiology of affective disorders.

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Organic Bipolar Disorder: An Unusual Neuropsychiatric Sequelae following Right Frontotemporal Injury

Cited by 4 publications

References 11 publications

Research on clinical aspects of bipolar disorder: A review of Indian studies

Research on clinical aspects of bipolar disorder: A review of Indian studies

Neuropsychiatry and Traumatic Brain Injury

Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review

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