The Upper Devonian to Mississippian was a very dynamic time in Earth’s history and encompassed substantial changes in widely separated palaeoenvironments. Major evolutionary trends did not occur through a long-lasting interval of ecological stability, instead they took place as recurring global events and/or crises of different magnitude, duration, and intensity. Framed by two of the most devastating time intervals – the Kellwasser and the Hangenberg crises – the Famennian has yielded other 2nd to 5th order events/crises. Many of these smaller scaled events show similarities with specific episodes of the longer-lasting crises and can especially be recognised in weakly tectonised pelagic facies that was present globally in a pan-tropical belt from North America to North Africa, Europe, Asia, and Australia. The search for causes of the Upper Devonian to Mississippian event/crisis sequence has made progress in the last few years. Nevertheless, we are still far from understanding all factors and reasons, which have triggered these environmental changes. The impact of Upper Devonian to Mississippian events/crises on faunal groups, such as ammonoids, has attracted many researches in past decades. Although, living in identical outer shelf settings, the different effects on conodonts have not yet received the attention they deserved in the context of our aim to understand the global environmental hazards of the past. One of the key questions is to understand, which and how environmental change influenced and/or stimulated the evolution of conodonts.