Organic Chemistry - II

Abstract

Numerous antibacterial silver compounds areusedinmedicine and hygiene. Thec ombination of silver and organicm aterials is important because of supramolecular or surface aspectsa nd thef ormationo fn anostructures. Therei sagrowing interest in exploitingt heir optoelectronica nd chemical properties which have potential applications in nanoelectronics [1] ,b ioanalytical processes [2] and catalysis. [3] To gain insight into moleculari nteractions of silver ions with peptidesw e used ac ombinatoriala pproach.W es ynthesized twoe ncodeds plit-and-mix peptide librariesc ontaining the amino acids D/L -Asp, D/L -Ser, D/L -His, L -Tyr( AAn), linear spacersl ikeG ly,ß -Ala,a minohexanoica cida nd turn inducing motives like Pro-Gly,P ro-Aib and trans -2-aminocyclohexane carboxylic acid ( Xn).