Organic chemistry of C60 (buckminsterfullerene): chromatography and osmylation

Abstract

Treatment of C60 with osmium tetroxide and pyridine gives the osmate ester (2:1 adduct) establishing that oxygen functionality can be added to C60 without disrupting the carbon framework.

Fullerenes

“…Среди этих соединений, которые получи-ли общее название «фуллероиды», можно отметить продукты присоединения радикалов водорода, фос-фора, галогенов, металлов и их окислов, одинарных и двойных бензольных колец и их производных, NO 2 [88 ], алкильных радикалов [89 ]. Особый интерес среди специалистов вызвала работа [90 ] [88 ]. При этом молекулы C 60 могут играть двоя-кую роль -либо в качестве основы полимерной це-почки, либо в качестве соединительного элемента.…”

The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer

“…It is thus essential to discover novel drugs and their targets to more selectively eradicate cancer cells. Within the pharmaceutically important heterocyclic compounds, the 1,2,3,4-tetrahydroquinoline and 1,2,3,4-tetrahydroisoquinoline ring systems are common structural motifs found in several biologically active compounds (2)(3)(4)(5)(6). The discovery and development of a novel class of 1,2,3,4-tetrahydroisoquinoline derivatives as selective anticancer drugs represent new challenges in the discovery and development of anticancer drugs.…”

Peer Reviewed: Chromatographic Separation of Fullerenes

“…More effective separation and isolation methods were demonstrated with chemically bonded stationary phases in HPLC. Hawkins and co-workers reported a phenylglycine-derivatized bonded phase for separating C 60 and C 70 (9). Cox and co-workers used dinitroanilinopropyl silica as the stationary phase (10).…”