Organic Chemistry of α-Methylstyrene. I. Reactions Leading to N-(α,α-Dimethyl-substituted-benzyl)acrylamides

Roberts, Carleton W.; Nuenke, Norman F.

doi:10.1021/jo01094a022

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2011

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Cited by 5 publications

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“…Compounds 3a [10], 3b [12], 3c [13], 3d [14], 3e [11], 3f [15], 3g [16], 3h [17], 3i [18] and 3j [19] represent the literature known compounds and their analytical data was in general agreement with the reported data. More detailed analytical data for 3d and 3f is given below.…”

Section: Methodssupporting

confidence: 73%

Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst

Streuff

Muñiz

2005

Journal of Organometallic Chemistry

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Section: Methodssupporting

confidence: 73%

Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst

Streuff

Muñiz

2005

Journal of Organometallic Chemistry

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TheRitter Reaction

Krimen

Cota

2011

Organic Reactions

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The formation of N‐substituted amides by the addition of nitriles to alkenes in the presence of concentrated sulfuric acid was first described by Ritter in 1948. The reaction has been extended to the addition of nitriles to a wide variety of compounds capable of forming a carbonium ion, and it constitutes the only really useful procedure for the preparation of amides of tertiary carbinamines. In its most general form, the Ritter reaction involves the nucleophilic addition of a nitrile to a carbonium ion in the presence of sulfuric acid. Attention has been given to reactions in which the carbonium ion is generated in sulfuric acid, or less commonly in sulfonic acids, phosphoric acids, or boron trifluoride. For comparison, analogous reactions, which are initiated by a nitrilium ion, formed from a nitrile and a Friedel‐Crafts catalyst, have been included in this chapter.

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Ritter-type Reactions

Bishop

1991

Comprehensive Organic Synthesis

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Organic Chemistry of α-Methylstyrene. I. Reactions Leading to N-(α,α-Dimethyl-substituted-benzyl)acrylamides

Cited by 5 publications

References 3 publications

Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst

Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst

TheRitter Reaction

Ritter-type Reactions

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