Organic Chiral Spin‐Optics: The Interaction between Spin and Photon in Organic Chiral Materials

Gao, Mingsheng; Qin, Wei

doi:10.1002/adom.202101201

Cited by 27 publications

(21 citation statements)

References 160 publications

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“…[27] One particular class of chiral nano metallic materials/magnetic-based systems are widely used as nanocarriers for drug delivery because of their magnetic recyclability and bacterial benignancy. [45][46][47][48][49] In this study, we report a simple wet protocol for the synthesis of superparamagnetic chiral Co superstructures (Co SS) that exhibit inherent antibacterial and bacterial binding characteristics. Herein, we used L/D-tartaric acid (L/D-Tar) as a chiral ligand, cobalt nitrate as a cobalt source, and hydrazine hydrate as a reducing agent.…”

Section: Doi: 101002/smll202204219mentioning

confidence: 99%

Six‐Pointed Star Chiral Cobalt Superstructures with Strong Antibacterial Activity

Wang

Hao

Chen

et al. 2022

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Chiral inorganic nanomaterials have shown promise as a potential means of combating bacteria due to their high levels of biocompatibility, easy surface modification, and excellent optical properties. In this study, a diverse range of chiral hierarchical nanomaterials are prepared from Co 2+ and L/D-Tartaric acid (Tar) ligands. By combining the ligands in different ratios, chiral Co superstructures (Co SS) are obtained with different morphologies, including chiral nanoflowers, chiral nanohanamaki, a chiral six-pointed star, a chiral fan shape, and a chiral fusiform shape. It is found that the chiral six-pointed star structures exhibit chiroptical activity across a broad range of wavelengths from 300 to 1300 nm and that the g-factor is as high as 0.033 with superparamagnetic properties. Under the action of electromagnetic fields, the chiral six-pointed star Co SS shows excellent killing ability against Gram-positive Staphylococcus aureus (ATCC 25923). Compared to L-Co SS, D-Co SS shows stronger levels of antibacterial ability. It is found that the levels of reactive oxygen species generated by D-Co SS are 1.59-fold higher than L-Co SS which is attributed to chiral-induced spin selectivity effects. These findings are of significance for the further development of chiral materials with antibacterial properties.

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Section: Doi: 101002/smll202204219mentioning

confidence: 99%

Six‐Pointed Star Chiral Cobalt Superstructures with Strong Antibacterial Activity

Wang

Hao

Chen

et al. 2022

Small

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“…It is a common belief that studying the molecular mechanism of protein folding, from the original (unfolded) homochiral polypeptide chain to native conformation, has represented one of the biggest challenges in biochemistry and molecular biology [ 109 , 110 , 111 , 112 , 113 ]. In this field, the most intense debates were and remain focused on the role of entropy in protein self-assembly, into nano and mesoscale structures [ 107 , 108 , 109 ].…”

Section: Epiloguementioning

confidence: 99%

“…In this field, the most intense debates were and remain focused on the role of entropy in protein self-assembly, into nano and mesoscale structures [ 107 , 108 , 109 ]. Experimental observation of the effects of electron-nuclear-photon spins coupling allows for the determination of the 3-D shape of the protein structure [ 110 ]. Resolving the protein structure, in turn, promotes the understanding of cell and organism physiology.…”

Section: Epiloguementioning

confidence: 99%

Arrow of Time, Entropy, and Protein Folding: Holistic View on Biochirality

Dyakin

Uversky

2022

IJMS

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Chirality is a universal phenomenon, embracing the space–time domains of non-organic and organic nature. The biological time arrow, evident in the aging of proteins and organisms, should be linked to the prevalent biomolecular chirality. This hypothesis drives our exploration of protein aging, in relation to the biological aging of an organism. Recent advances in the chirality discrimination methods and theoretical considerations of the non-equilibrium thermodynamics clarify the fundamental issues, concerning the biphasic, alternative, and stepwise changes in the conformational entropy associated with protein folding. Living cells represent open, non-equilibrium, self-organizing, and dissipative systems. The non-equilibrium thermodynamics of cell biology are determined by utilizing the energy stored, transferred, and released, via adenosine triphosphate (ATP). At the protein level, the synthesis of a homochiral polypeptide chain of L-amino acids (L-AAs) represents the first state in the evolution of the dynamic non-equilibrium state of the system. At the next step the non-equilibrium state of a protein-centric system is supported and amended by a broad set of posttranslational modifications (PTMs). The enzymatic phosphorylation, being the most abundant and ATP-driven form of PTMs, illustrates the principal significance of the energy-coupling, in maintaining and reshaping the system. However, the physiological functions of phosphorylation are under the permanent risk of being compromised by spontaneous racemization. Therefore, the major distinct steps in protein-centric aging include the biosynthesis of a polypeptide chain, protein folding assisted by the system of PTMs, and age-dependent spontaneous protein racemization and degradation. To the best of our knowledge, we are the first to pay attention to the biphasic, alternative, and stepwise changes in the conformational entropy of protein folding. The broader view on protein folding, including the impact of spontaneous racemization, will help in the goal-oriented experimental design in the field of chiral proteomics.

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“…[2][3][4] Recently, chiral materials have attracted increasing interest due to their potential application in sensorics, optoelectronics and spintronics. [5][6][7] At present, a variety of organic-only/organic-inorganic chiral films and nanostructures have been designed through self-assembly processes. 8,9 These chiral materials exhibit interesting physical properties such as circular dichroism (CD), [10][11][12][13][14] circularly polarized photoluminescence, 15 nonlinear optical effects, 2 ferroelectricity, 16 and bulk photovoltaic effects.…”

Section: Introductionmentioning

confidence: 99%