Organic/Inorganic bioactive materials Part II: in vitro bioactivity of Collagen-Calcium Phosphate Silicate/Wollastonite hybrids

Abstract

Abstract:In the present study, novel hybrid materials of Collagen (C) and Calcium Phosphate Silicate/Wollastonite (CPS/W) were synthesized.The CPS/W ceramic was prepared via polystep sol-gel method. The dissolution test of CPS/W ceramic was filled with TRIS-HCl buffer. FTIR depicts that hydroxyl carbonate apatite (OHCO 3 HA) was observed after 3 days of immersion in TRIS-HCl buffer. Biohybrids of C-CPS/W were produced from diluted hydrochloric acid collagen type I and ceramic powder with different ratios of C and CPS/W equal to 25:75 and 75:25 wt.%. The synthesized hybrids were characterized by FTIR, XRD and SEM. FTIR depicts a "red shift" if amide I could be attributed to the fact that the collagen prefers to chelate Ca 2+ from partial dissolution of CPS/W ceramic. The growth of B-type carbonate containing hydroxyapatite (B-CO 3 HA) on the C-CPS/W hybrids soaked in 1.5SBF was observed. The negatively charged carboxylate groups from the collagen may be responsible for hydroxyapatite (HA) deposition. This fact was confirmed by the "red shift" of carboxylate groups of collagen in FTIR spectra. The formation of HA was observed by FTIR, XRD and SEM.© Versita Warsaw and Springer-Verlag Berlin Heidelberg.

Porous Bioactive Glass Scaffolds for Local Drug Delivery in Osteomyelitis: Development and In Vitro Characterization

“…The emergence of these two peaks could be due to the absorption of CO 2 from atmosphere even after thermal treatment. A similar observation has been reported with calcium phosphate silicate/wollastonite (12), and hence, storage in dessicator is advised. XRD patterns (Fig.…”

Biocomposites and hybrid biomaterials based on calcium orthophosphates

“…glass-reinforced HA/polyacrylate 1068 as well as collagen 1069 and gelatin 1070 calcium phosphate silicate/wollastonite biocomposites. HA/glass biocomposites can be prepared by simple sintering of appropriate HA/glass powder mixtures.…”

<i>In </i><i>V</i><i>itro</i>Bioactivity of Collagen/Calcium Phosphate Silicate Composites, Cross-Linked with Chondroitin Sulfate

“…First of all, in the spectrum of pure collagen (data are not shown here), the amide I peak centered at 1656 cm -1 predominantly corresponds to the C=O stretch vibration [12]. From the other studies, the amide I band in a bone spectrum is representative of the collagen content and structure [18].…”

“…We observed that the prepared ceramics were in vitro bioactive for different periods of time. On this base we have prepared in vitro bioactive composites with some biodegradable polymers without [12][13][14][15] and with [16] cross-linkage.…”