Summary. The aim of the study is, on the basis of research and analysis of current normative and methodological documents, to develop proposals for the improvement of regulation and methodological support of the system for the organization of medical assistance to victims and their medical evacuation in emergencies at facilities and territories served by the Federal Medical and Biological Agency (FMBA of Russia). Study materials and methods. Materials of the study include legislative acts and regulatory documents in force in the field of healthcare in the country, including the system of FMBA of Russia, on the problem under study; orders and guidelines of FMBA of Russia on the organization of medical care to victims and their medical evacuation in emergencies; scientific papers and publications devoted to current issues of regulation and methodological support of medical and evacuation support of victims in emergencies. The following methods were applied: historical; methods of content analysis and expert review, logical and information modeling; analytical method. Results of the study and their analysis. The article presents the results of the study and analysis of the principal regulatory and methodological documents governing the organization of medical aid and medical evacuation of the victims of emergencies at the facilities and territories served by the Federal Medical and Biological Agency and the medical forces and facilities of the Functional Subsystem of the Federal Medical and Biological Agency. The backlogs of these documents are demonstrated. Proposals for further improvement of legal regulation and methodological support of activities of the functional subsystem of FMBA of Russia are made.