This article examines the correlates of Vietnamese social work practitioners’ attitudes toward individuals who identify as lesbian or gay. This study, among the very few studies on the general topic in non-Western contexts and the first of its kind in Vietnam, investigates correlates of attitudes toward sexual minorities that are known in the literature. The data are drawn from a survey of 292 Vietnamese social work practitioners. The findings suggest that the attitudes of Vietnamese social work practitioners are associated with gender, educational attainment, level of social work education, practice experience, practice sector, professional contact with sexual minority clients, personal contact with sexual minorities, exposure to content on sexual minorities in social work courses and professional development activities, and independent learning activities about sexual minorities but not with age, religious affiliation, and marital status. Implications for social work education and practice are considered.