Nowadays, society faces challenges like climate change and inequality that are addressed by the Sustainable Development Goals. Academia plays a central role as a driver for innovation through research, teaching, and transfer to develop answers to these challenges. Responsible Research and Innovation (RRI) provides a framework for aligning research and innovation with societal needs. The technical university RWTH Aachen University considers RRI to be one of its main principles and established the RRI Hub as part of its excellence strategy in 2019. The RRI Hub is supposed to strengthen RRI in research, teaching, and transfer, with a focus on sustainable and responsible development, social innovation, and sustainable and inclusive artificial intelligence. This article describes the importance of academia to foster RRI and to structurally integrate it into universities using the example of the RRI Hub at the technical university RWTH Aachen. As a case, a participatory research project in the area of RRI is presented additionally.