Organizing pneumonia. Features and prognosis of cryptogenic, secondary, and focal variants

Lohr, Robert H.; Boland, Benoît; Douglas, W. W.; Dockrell, David H.; Colby, Thomas V.; Swensen, Stephen J.; Wollan, Peter C.; Silverstein, Marc D.

doi:10.1001/archinte.157.12.1323

Cited by 141 publications

(235 citation statements)

References 29 publications

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“…Hastalığın başlangıç yaşı 20-80 yıl arasında geniş bir dağılım gösterirken, ortalama 55'tir. 2,3,6 Klinik bulgular genellikle subakut seyir göstermektedir; kuru öksürük, nefes darlığı, ateş, hâlsizlik ve kilo kaybı en sık saptanan belirtilerdir. Göğüs ağrısı, gece terlemesi, hemoptizi, artralji nadiren bulunabilmektedir.…”

Section: Discussionunclassified

“…Klinik ve radyolojik bulgular, hem sekonder hem kriptojenik OP'de benzerdir. 2 Olgumuz da 29 yaşında idi ve sigara içmemişti. Yaklaşık 2 aydır olan ve giderek artan efor dispnesi mevcuttu.…”

Section: Discussionunclassified

“…KAVİTER SEKONDER ORGANİZE PNÖMONİ: NADİR BİR ANTİTE Turkiye Klinikleri Arch Lung 2016;17 (2) trüktif pnömoni, apse, aspirasyon pnömonisi, kistik fibroz, pnömokonyoz, plevral plak gibi başka patolojilerin komşuluğunda da OP saptanabilmektedir. 1 Tipik radyolojik görünüme sahip çoğu hastada transbronşiyal biyopsi ile alınan örneklerde karakteristik intraalveolar tomurcukların görül-mesi tanı için yeterli olabilmektedir.…”

Section: Discussionunclassified

“…Herhangi bir neden veya altta yatan hastalık bulunamadığında ise kriptojenik organize pnömoni (KOP) olarak sı-nıflandırılmaktadır. [1][2][3][4] OP'ye neden olan etiyolojik nedenin araştırılması tedavi yaklaşımı açısından önemlidir. Tipik radyolojik görünüm en sık periferik, değişik boyutlarda multifokal konsolidasyonlardır.…”

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Cavitary Secondary Organizing Pneumonia: A Distinct Clinical Entity: Case Report

Kuver¹,

Akyil²,

Akyıl³

et al. 2016

Turkiye Klinikleri Arch Lung

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Section: Discussionunclassified

unclassified

See 2 more Smart Citations

Cavitary Secondary Organizing Pneumonia: A Distinct Clinical Entity: Case Report

Kuver¹,

Akyil²,

Akyıl³

et al. 2016

Turkiye Klinikleri Arch Lung

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“…2). 21,22 The underlying lung architecture is preserved, and the regions of alveolar consolidation are often patchy and frequently bronchiolocentric. The fibrous plugs are rich in mucopolysaccharides and have a slight basophilic appearance on hematoxylin and eosin staining (rather than the eosinophilic appearance seen with established dense fibrosis in scar tissue).…”

Section: Pathologymentioning

confidence: 99%

Imaging of Acute Lung Injury

Elicker¹,

Jones

Naeger

et al. 2016

Radiologic Clinics of North America

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Nodular Diseases

2006

Diffuse Lung Diseases

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The subacute form of hypersensitivity pneumonitis (HP) tipically presents a nodular pattern. HP represents a group of diffuse granulomatous parenchymal lung diseases caused by the repeated inhalation of, and sensitization to, a broad variety of low molecular weight organic antigens and chemicals. Clinical presentation may be acute (HP, acute) or chronic (HP, chronic) Extrinsic Allergic Alveolitis (EAA) DEMOGRAPHICS The number of responsible inciting antigens is high (more than 300) and new antigens are constantly being identified. The most commonly known diseases are "Farmer's lung", caused by the inhalation of Faeni rectivirgula present in moldy hay and "Bird fancier's lung", caused by exposure to avian proteins. The subacute form of the disease seems to be produced by a less intense exposure to the inciting antigen than occurs in the acute form. Gell and Coombs type III and type IV immune reactions lie at the basis of the immunopathogenesis of the disease The incidence and prevalence of the disease is difficult to estimate, since individual susceptibility, intensity of exposure in different occupational settings, seasons, geographical areas and proximity of industry vary greatly. The prevalence of "Farmer's lung" varies between 2 and 9%, whereas that of "Bird fancier's lung" varies between 6 and 15% Non-smokers are more commonly affected CLINICAL FEATURES Onset in the subacute form is insidious, with symptoms characterized by slowly worsening cough, dyspnea, fatigue, anorexia and weight loss. Acute exacerbation of symptoms occasionally occurs. In contrast to the acute form, clinical history is not always able to identify a temporal correlation (4-12 h) between onset of symptoms and exposure to the inciting agent (e.g. moldy hay, avian proteins, etc.) Diffuse fine bibasilar rales are often noted on physical examination. Patients may present signs of wasting Patterns include moderate-to-severe restrictive defects and mixed restrictive and obstructive defects. There is hypoxemia at rest and D L CO is reduced in most cases

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Organizing pneumonia. Features and prognosis of cryptogenic, secondary, and focal variants

Cited by 141 publications

References 29 publications

Cavitary Secondary Organizing Pneumonia: A Distinct Clinical Entity: Case Report

Cavitary Secondary Organizing Pneumonia: A Distinct Clinical Entity: Case Report

Imaging of Acute Lung Injury

Nodular Diseases

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