“…[36][37][38][39][40] Although synthetically easily available and featured in numerous natural products and bioactive molecules, tetramic acids, i. e. pyrrolidine-2,4-dione derivatives, have only once been employed as a substrate in an organocatalyzed transformation. [41] Pyrrolidine-2,3dione [42][43] and pyrrolidine-2,5-dione [44] derivatives have, similarly, seen limited application in organocatalyzed reactions. In continuation of our research on the implementation of pyrrolone derivatives in organocatalyzed asymmetric transformations, [45][46][47][48][49] we herein report the application of N-substituted tetramic acids 3 in the organocatalyzed conjugative addition to nitroalkene acceptors, followed by O-alkylation.…”