Organochlorine Pesticides Exposure in Children From the Agricultural Zone of San Luis Potosí, México

Perez, N.; Acevedo, A Trejo; Maldonado, Iván Nelinho Pérez; Díaz‐Barriga, Fernando; Amador, Diana Rocha; Estrada, Lindsay

doi:10.1097/01.ede.0000276881.06361.e7

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“…In addition, their solubility in lipids contributes to their bioaccumulation and biomagnification through food chains, increasing the potential risk to human health [ 6 ]. Exposure to OC pesticides increases health risks such as propensity to develop of cancer [ 7 ], reproductive effects [ 8 ], behavioral and neurological effects [ 9 ], and genotoxic effects [ 10 , 11 ]. There is also evidence that low-dose exposure to OC pesticides can be a risk factor for type 2 diabetes.…”

Section: Introductionmentioning

confidence: 99%

Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico

Ruiz-Suárez

Castro-Chan

Rivero-Pérez

et al. 2014

IJERPH

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Organochlorine (OC) pesticides have been extensively used for pest control in agriculture and against malaria vectors in the region of Soconusco, Chiapas, in southern Mexico. Our study aimed to identify whether the inhabitants of four Soconusco communities at different locations (i.e., altitudes) and with different history of use of OC pesticides, have been similarly exposed to residues of these pesticides. In particular, we analyzed the potential relationship between levels of OC pesticides in plasma and the age, gender, and residence of the study population (n = 60). We detected seven pesticides in total (γ-HCH, β-HCH, OPEN ACCESS Int. J. Environ. Res. Public Health 2014, 1110445 heptachlor, p,pʹ-DDE, p,p'-DDT, β-endosulfan, endrin aldehyde). Of these, p,pʹ-DDE and β-endosulfan were the most frequently found (in 98% and 38% of the samples, respectively). The low-altitude (<20 m above sea level; masl) and mid-altitude (520 masl) locations had the highest levels of p,pʹ-DDE, with geometric means of 50.6 µg/L and 44.46 µg/L, respectively. The oldest subjects (>60 years) had the highest p,pʹ-DDE level (56.94 ± 57.81 µg/L) of all age groups, while men had higher p,pʹ-DDE (34.00 ± 46.76 µg/L) than women. Our results demonstrate that residents of the Soconusco region are exposed to p,pʹ-DDE because of high exposure to DDT in the past and current environmental exposure to this DDT-breakdown product.

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Section: Introductionmentioning

confidence: 99%