Organogermanium Chemistry.

Quane, D.; Bottei, R.S.

doi:10.1021/cr60224a004

Cited by 59 publications

(7 citation statements)

References 111 publications

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“…It should be mentioned that several excellent current reviews are available for initial perusal which cover the major portion of Group IVB chemistry in genera1. [60][61][62][63][64][65][66][67][68][69][70]…”

Section: Organometallic Estersmentioning

confidence: 99%

Organometallic Polymers

Henry

Davidson

1965

Annals of the New York Academy of Sciences

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Section: Organometallic Estersmentioning

confidence: 99%

Organometallic Polymers

Henry

Davidson

1965

Annals of the New York Academy of Sciences

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“…For example, organogermane can be unstable in the presence of electrophiles as well as nucleophiles. 51 Under hydrogenation conditions, these groups may promote the defunctionalization or even could lead to reaction termination. Another major challenge during hydrogenation is to control the diastereoselectivity as reduction of functionalized arenes can generate multiple stereocenters.…”

Section: ■ Introductionmentioning

confidence: 99%

cis-Selective Hydrogenation of Aryl Germanes: A Direct Approach to Access Saturated Carbo- and Heterocyclic Germanes

et al. 2023

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A catalytic approach of synthesizing the cis-selective saturated carbo-and heterocyclic germanium compounds (3D framework) is reported via the hydrogenation of readily accessible aromatic germanes (2D framework). Among the numerous catalysts tested, Nishimura's catalyst (Rh 2 O 3 /PtO 2 •H 2 O) exhibited the best hydrogenation reactivity with an isolated yield of up to 96%. A broad range of substrates including the synthesis of unprecedented saturated heterocyclic germanes was explored. This selective hydrogenation strategy could tolerate several functional groups such as −CF 3 , −OR, −F, −Bpin, and −SiR 3 groups. The synthesized products demonstrated the applications in coupling reactions including the newly developed strategy of aza-Giese-type addition reaction (C−N bond formation) from the saturated cyclic germane product. These versatile motifs can have a substantial value in organic synthesis and medicinal chemistry as they show orthogonal reactivity in coupling reactions while competing with other coupling partners such as boranes or silanes, acquiring a three-dimensional structure with high stability and robustness.

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“…benzylpotassium. 15,16 To examine this possibility, we have conducted an experiment with the use of benzylsodium, in which we observed that BnNa was able to initiate hydrogermylation. In the next step, VIII attacks a styrene molecule at the terminal carbon atom and produces a carbanion (IX-XI).…”

mentioning

confidence: 99%