Organometallic derivatives. Part IV. The lithiation of ferrocenylmethyl phenyl sulphone and the cleavage of carbon–sulphur bonds by aniline

Stereoselective alkylation of [2-(diphenylphosphino)ferrocenyl]acetonitrile

“…In ferrocene chemistry, selective a-deprotonation of ferrocenylacetonitrile followed by alkylation (with RX) to give doubly substituted nitriles FcCR 2 CN has been reported as early as in 1973 (Fc = ferrocenyl) [3]. (Ferrocenylmethyl)phenylsulfone FcCH 2 SO 2 Ph [4] and phosphine chalcogenides FcCH 2 P(E)Ph 2 (E = O and S) [5] were shown to behave similarly. To the best of our knowledge, these reactions were not studied further nor found utilization in the synthesis of other ferrocene derivatives.…”