Organotin contamination, imposex and androgen/oestrogen ratios in natural populations of <i>Nassarius reticulatus</i> along a ship density gradient

Barroso, Carlos M.; Reis-Henriques, M.A.; Ferreira, Marta; Gibbs, Peter; Moreira, M. H.

doi:10.1002/aoc.955

Cited by 20 publications

(8 citation statements)

References 17 publications

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“…A negative correlation was found between aromatase activity and organotin body burden. Barroso et al (2005) analyzed organotin body burdens, imposex and steroid hormone levels (T, T glucuronide, T sulfate conjugates, and E2) in natural populations of N. reticulatus from Portugal between 1997 and 1999. T levels in females without imposex were always lower than in females with imposex, and the T/E2 ratio tended to increase with increasing imposex and organotin contamination.…”

Section: Aromatase Inhibitionmentioning

confidence: 99%

Endocrine disruption in prosobranch molluscs: evidence and ecological relevance

et al. 2007

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Prosobranch snails represent almost 50% of all recent molluscs, are ubiquitously distributed, play important roles in various ecosystems and exhibit a variety of reproductive modes and life-cycle-strategies. Many of them attain life spans of several years, which in combination with their limited ability to metabolize organic chemicals, may contribute to the fact that prosobranchs constitute one of the most endangered taxonomic groups in aquatic ecosystems. Although it is not yet known to what extent endocrine disrupting chemicals (EDCs) contribute to this situation, the case of tributyltin (TBT) and its population-level impact on prosobranchs demonstrates the general susceptibility of these invertebrates. The existing evidence for comparable population-level effects in prosobranch snails by other androgens, antiandrogens, and estrogens is critically reviewed. The example of TBT demonstrates the difficulty to prove an endocrine mode of action for a given chemical. Although it is generally accepted that TBT causes imposex and intersex in prosobranch snails as a result of endocrine disruption, the detailed biochemical mechanism is still a matter of debate. The strengths and weaknesses of the five competing hypotheses are discussed, together with previously unpublished data. Finally, the ecological relevance of EDC effects on the population and community level and the application of prosobranchs for the assessment of EDCs are addressed.

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Section: Aromatase Inhibitionmentioning

confidence: 99%

Endocrine disruption in prosobranch molluscs: evidence and ecological relevance

et al. 2007

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“…Barreiro et al (2001Barreiro et al ( , 2004; Ruiz et al (2005), Quintela et al (2006), Couceiro et al (2009) and Rodríguez et al (2009 Coastal areas along the continental Portuguese coast Gibbs et al (1997); Barroso et al (2000Barroso et al ( , 2001Barroso et al ( , 2005; Pessoa et al (2001); Sousa et al (2005bSousa et al ( , 2007bSousa et al ( , 2009b, Rato et al (2009) VDSI Vas deferens sequence index. Classifies the degree of females' masculinization and is considered as the most valid index to assess tributyltin pollution as, in extreme cases, it can express the reproductive capacity of the population (Stroben et al 1992b) (Fig.…”

Section: Aosmentioning

confidence: 99%

“…Stage 4+ was considered as the end of imposex development in the nassarid in the initial scheme proposed by Stroben et al (1992b), however some authors proposed the computation of stage 4+ to 4.5 (Barreiro et al 2001) or to 5 in order to better discriminate between highly polluted locations. The majority of recent reports use the latter (Barroso et al 2005;Laranjeiro et al 2010;Rato et al 2008Rato et al , 2009Rodríguez et al 2009;Ruiz et al 2005;Sousa et al 2005bSousa et al , 2007aSousa et al , 2009b. …”

Section: Aosmentioning

confidence: 99%

Pollutant Diseases, Remediation and Recycling

2013

Environmental Chemistry for a Sustainable World

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“…This damage occurs by morphological and biological changes (Alzieu et al 1981;Fioroni et al 1991;Schulte-Oehlmann et al 1997;Horiguchi et al 1998) such as the imposex phenomenon defined by the development of male characteristics in females under the influence of very low concentrations of TBT and TPT (from 0.4 ng L À1 ) (Huet et al 2004). Affected females show high levels of free testosterone compared with normal ones (Spooner et al 1991;Bettin et al 1996;Gooding et al 2003; Barroso et al 2005;Santos et al 2006). These trisubstituted compounds (TBT and TPT) act as neurotoxins that inhibit the release of a neuroendocrine factor of pleural ganglia, penis regressive factor (PRF), which prevents the formation of this organ in females (Barroso et al 2002;Horiguchi et al 2006;Santos et al 2006).…”

Section: Introductionmentioning

confidence: 99%

Biomonitoring of the environmental contamination by organotins in the Gulf of Tunis: occurrence of imposex in Stramonita haemastoma (Linnaeus, 1767)

Boulajfene

Boukhicha

Deidun

et al. 2015

Mar. Freshwater Res.

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Imposex has been observed in several regions of the world to affect many species of prosobranch gastropods such as Stramonita haemastoma (Linnaeus, 1767). This irreversible sexual anomaly is caused mainly by the accumulation of organotin compounds in tissues. The present study aimed to confirm the existence of imposex and to determine the different levels of infection in individuals of Stramonita haemastoma collected from different stations along the rocky coastline of the Gulf of Tunis. To do this, 10 stations covering the entire rocky coastline of the gulf were sampled during March-May 2012. Rates of occurrence of imposex suggest that sexual modifications occur to different degrees in this species in all sampled stations of the gulf. The most contaminated sites were harbour areas (Sidi Bou Said and La Goulette). In addition, an inverse relationship between the distances from potential sources of pollution and the occurrence of this sexual anomaly was observed. It should be noted that toxic effects induced by marine xenobiotics could cause the loss of biodiversity and the disruption of this ecosystem stability.

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Organotin contamination, imposex and androgen/oestrogen ratios in natural populations of Nassarius reticulatus along a ship density gradient

Cited by 20 publications

References 17 publications

Endocrine disruption in prosobranch molluscs: evidence and ecological relevance

Endocrine disruption in prosobranch molluscs: evidence and ecological relevance

Pollutant Diseases, Remediation and Recycling

Biomonitoring of the environmental contamination by organotins in the Gulf of Tunis: occurrence of imposex in Stramonita haemastoma (Linnaeus, 1767)

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