Organotin(IV) complexes with pyruvic acid phenylhydrazone (HPAPD): synthesis, spectral characterization, and in vitro antibacterial activity

Diorganotin(IV) complexes of 3,5-dichloro-2-hydroxybenzaldehyde-N(4)-ethylthiosemicarbazone: Synthesis, spectral characterization and crystal structure

“…The aromatic protons of the ligand and its complexes were observed in the region of 8.12-7.62 ppm. For complex 2, the resonance signal of the two methyl groups attached to tin(IV) centre appears at 1.02 ppm with 2 J [ 119 Sn, 1 H] of 86.31 Hz confirming five coordinated tin(IV) atom and similar to those previously reported [44,45]. The signals observed in the region at 3.67-3.61 and 1.16-1.10 ppm have been assigned to the (-CH 2 ) and (-CH 3 ) protons of the ligand and its complexes, respectively.…”

Crystal structure of (E)-2-[3-(tert-butyl)-2-hydroxybenzylidene]-N-cyclohexylhydrazine-1-carbothioamide

“…Such Schiff bases are of special interest because of their specific coordinating ability to some metal ions (Arion et al, 2001;Leovac & Č ešljević, 2002;Chandra & Sangeetika, 2004;Singh et al, 2000;Gerbeleu et al, 2008;Mohamed et al, 2009). Several reports have highlighted the importance of the chelate metal complexes of thiosemicarbazone Schiff bases for medicinal applications, particularly against cancer (Paterson & Donnelly, 2011;Ziessel, 2001;Salam et al, 2012;Arafath et al, 2017a). Thus thiosemicarbazones with ONS coordinating sites are important in coordination chemistry because of their strong bonding ability to transition metal ions as well as because of their pharmaceutical uses (Rayati et al, 2007;Alomar et al, 2009;Vieites et al, 2009).…”

Schiff base‐nickel, palladium, and platinum complexes derived from N‐cyclohexyl hydrazine carbothioamide and 3‐hydroxy‐4‐methoxybenzaldehyde: Selective antiproliferative and proapoptotic effects against colorectal carcinoma

“…Schiff bases and their metal complexes are versatile compounds in coordination chemistry with vast applications. Several reports have highlighted the importance of the metal complexes for medicinal applications, particularly against cancer (Arafath et al, ; Salam, Affan, Ahmad, & Arafath, ; Ziessel, ). Derivatives of Schiff bases have attracted a great deal of attention due to the presence of hard and soft atoms together in a single molecule, such as thiosemicarbazone Schiff bases having sulfur, a soft atom together with nitrogen and oxygen, which are hard atoms (Mohamed, Omar, & Ibrahim, ).…”