Organotin pollution in China: An overview of the current state and potential health risk

Cao, Dandan; Jiang, Guibin; Zhou, Qunfang; Yang, Ruiqiang

doi:10.1016/j.jenvman.2008.06.007

Cited by 108 publications

(43 citation statements)

References 65 publications

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“…4 Their toxic effects are observed in many species because tributyltin (TBT) can induce an endocrine disruption process known as imposex. 5 This effect in mollusks has been well documented. [6][7][8] Other effects caused by TBT include shell malformation in the Pacific oyster Crassostrea gigas, suppressed growth in the centric diatoms Skeletonema costatum and Thalassiosira pseudonana and increased mortality in the sabellid Sabellastarte sanctijosephi, among other marine organisms affected.…”

Section: Introductionmentioning

confidence: 89%

Tributyltin in crustacean tissues: analytical performance and validation of method

Cristale

Santos

Sant’Anna

et al. 2012

J. Braz. Chem. Soc.

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O ermitão Clibanarius vittatus é um organismo típico de regiões intertidais estuarinas sendo considerado um possível bioindicador da presença de tributilestanho (TBT) nesses ambientes. Por esta razão, este estudo apresenta o desempenho analítico e a validação do método para quantificação de TBT em tecidos de C. vittatus por cromatografia gasosa com detector fotométrico de chama pulsante (GC-PFPD), após extração com solvente apolar (tolueno) e derivatização com reagente de Grignard. Os limites de detecção do método (LOD) foram 2,0 e 2,8 ng g -1 para TBT e DBT (dibutil estanho), respectivamente, e seus limites de quantificação (LOQ) 6,6 e 8,9 ng g -1 para TBT e DBT, respectivamente. O método foi aplicado em amostras do Estuário de Santos, Estado de São Paulo, Brasil. As concentrações de TBT e DBT variaram de 26,7-175,0 ng g -1 a 46,2-156,0 ng g -1 , respectivamente. As concentrações encontradas saopreocupantes uma vez que efeitos tóxicos (tais como a alteração endócrina) têm sido relatados em outros organismos, mesmo em níveis inferiores aos registrados no presente estudo.The hermit crab Clibanarius vittatus is a typical organism from intertidal regions being considered as a good bioindicator of tributyltin presence at these environments. Thus this study presents the analytical performance and validation method for TBT quantification in tissues of C. vittatus by gas chromatography with pulsed flame photometric detector (GC-PFPD) after extraction with an apolar solvent (toluene) and Grignard derivatization. The limits of detection of the method (LOD) were 2.0 and 2.8 ng g -1 for TBT and DBT (dibutyltin), respectively, and its limits of quantification (LOQ) were 6.6 and 8.9 ng g -1 for TBT and DBT, respectively. The method was applied to samples from Santos Estuary, São Paulo State, Brazil. TBT and DBT concentrations ranged from 26.7 to 175.0 ng g -1 and from 46.2 to 156.0 ng g -1 , respectively. These concentrations are worrisome since toxic effects (such as endocrine disruption) have been reported for other organisms even under lower levels of registred at this study.Keywords: crustaceans, organotin, tributyltin (TBT), gas chromatography IntroductionButyltin compounds (BTs), members of the class of organometallic contaminants, are found in coastal regions worldwide because they were used in antifouling paints for many years. [1][2][3] In spite of the total worldwide ban proposed by the International Maritime Organization (IMO) in January 2008, these compounds are still found in different environmental compartments of aquatic systems. 4 Their toxic effects are observed in many species because tributyltin (TBT) can induce an endocrine disruption process known as imposex. 5 This effect in mollusks has been well documented. [6][7][8] Other effects caused by TBT include shell malformation in the Pacific oyster Crassostrea gigas, suppressed Tributyltin in Crustacean Tissues: Analytical Performance and Validation of Method J. Braz. Chem. Soc. 40 growth in the centric diatoms Skeletonema costatum and Thalassiosira pse...

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Section: Introductionmentioning

confidence: 89%

Tributyltin in crustacean tissues: analytical performance and validation of method

Cristale

Santos

Sant’Anna

et al. 2012

J. Braz. Chem. Soc.

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“…While the use of tributyltin (TBT) as antifouling agent has been banned since the late 1980s in most Europe and North America, TBT is still the commonly used active ingredients of antifouling paints in China (Fu et al 2003b) and Hong Kong (Kwok and Leung 2005). Cao et al (2009) estimated that the average annual organotin consumption in China is about 7500 tons.…”

Section: Introductionmentioning

confidence: 99%

Responses of growth and hemolymph quality in juvenile Chinese horseshoe crab Tachypleus tridentatus (Xiphosura) to sublethal tributyltin and cadmium

et al. 2015

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Responses of growth endpoints and hemolymph constituents in juvenile Chinese horseshoe crab Tachypleus tridentatus under treatments of 0.01 and 0.1 mg/l tributyltin (TBT) and 0.1 and 1 mg/l cadmium (Cd) were examined in a 12-week experiment. A significant decline in final body weight, final prosomal width, percentage of individuals molted and mean molting time was detected under TBT exposures. While morphological abnormalities of the juveniles between TBT treatments and the control were statistically indistinguishable, significantly higher occurrences of carapace erosion and appendage loss were noted under 0.1 and 1 mg/l Cd exposures. Various hemolymph quality indicators, including hemolymph plasma protein level, amebocyte viability and percentage of granular-spherical state of amebocytes of the juveniles exposed to TBT or Cd were significantly lower than the control. Such a decrease in hemolymph quality suggested deleterious effects of metal contaminant-induced stressors on the health status of the juveniles even at low exposure levels (i.e., 0.01 mg/l TBT and 0.1 mg/l Cd). Changes of hemolymph parameters in juvenile horseshoe crabs were more sensitive than growth performance as well as morphological abnormalities in response to metal stressors, and can be used as an indicator to reflect habitat conditions and contaminant levels.

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“…Due to the environmental effects of TBT, restrictions on the use on vessels less than 25m were imposed, first in France, then in the United Kingdom and in almost all developed countries during the eighties (Alzieu, 1991(Alzieu, , 1996Bosselmann, 1996;Champ, 2000;Yebra et al, 2004). However, TBT pollution still persists in the marine environments of many countries (Murai et al, 2005;Shi et al, 2005;Cao et al, 2009;Strand et al, 2009;Gipperth, 2009). Due to the effectiveness of TBT-based paints, the absence of an equivalent substitute (Chambers et al, 2006) and also the persistence of these compounds in sediments (Fernandez et al, 2005;Godoi et al, 2003;Santos et al, 2009), a large amount of TBT containing waste is still being produced around ports (Kotrikla, 2009).…”

Section: Introductionmentioning

confidence: 99%

Penis Malformations in Leucozonia nassa (Gmelin, 1792) and Leucozoniaocellata (Gmelin, 1791) in a TBT Contaminated Region from Brazil

Costa¹,

Mardegan²,

Zamprogno³

et al. 2014

AST

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Gastropod molluscs have potential for bioaccumulation of the organotin compounds (OTs) as tributyltin (TBT) and/or triphenyltin (TPT), used in antifouling paints applied to the hulls of ships to prevent biofouling. In gastropods, TBT may act as endocrine disruptors, and to induce imposex, impairing their reproductive capacity. The present study aimed to verify the occurrence of malformations, such as biphalic and triphalic penis in males and females with imposex in Leucozonia nassa and L. ocellata collected in Espírito Santo Bay between the years 2007 and 2011. During this period, 94.8% of female L. nassa and 24.5% of female L. ocellata exhibited imposex and 10 animals presented malformations. For L. nassa, malformations were found in seven females and one male, and for L. ocellata in two males. Most females with malformations presented VDSI stage ≥4 and these results indicate high levels of TBT contamination in the Espirito Santo Bay.

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Organotin pollution in China: An overview of the current state and potential health risk

Cited by 108 publications

References 65 publications

Tributyltin in crustacean tissues: analytical performance and validation of method

Tributyltin in crustacean tissues: analytical performance and validation of method

Responses of growth and hemolymph quality in juvenile Chinese horseshoe crab Tachypleus tridentatus (Xiphosura) to sublethal tributyltin and cadmium

Penis Malformations in Leucozonia nassa (Gmelin, 1792) and Leucozoniaocellata (Gmelin, 1791) in a TBT Contaminated Region from Brazil

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